CAJ | 학술논문

目的：分析加用参附注射液对冠心病慢性心力衰竭患者福辛普利应用剂量的影响。方法：以冠心病慢性心力衰竭急性发作的住院患者为研究对象，随机将其分为加用参附注射液的观察组（n＝26）和不加参附注射液的对照组（ n＝23），根据2组福辛普利应用剂量、平均动脉血压、血肌酐、血尿素氮等指标，分析加用参附注射液对福辛普利应用的影响。结果：观察组福辛普利应用剂量明显高于对照组（ P＜0.05），且对平均动脉血压、血肌酐、血尿素氮等指标无显著影响（ P＞0.05）。结论：在冠心病慢性心力衰竭急性发作的住院患者中，应用参附注射液显著增加福辛普利的应用剂量，且对血压及肾功能无明显影响，从而更早、更积极地启动神经激素阻滞治疗。
목적：분석가용삼부주사액대관심병만성심력쇠갈환자복신보리응용제량적영향。방법：이관심병만성심력쇠갈급성발작적주원환자위연구대상，수궤장기분위가용삼부주사액적관찰조（n＝26）화불가삼부주사액적대조조（ n＝23），근거2조복신보리응용제량、평균동맥혈압、혈기항、혈뇨소담등지표，분석가용삼부주사액대복신보리응용적영향。결과：관찰조복신보리응용제량명현고우대조조（ P＜0.05），차대평균동맥혈압、혈기항、혈뇨소담등지표무현저영향（ P＞0.05）。결론：재관심병만성심력쇠갈급성발작적주원환자중，응용삼부주사액현저증가복신보리적응용제량，차대혈압급신공능무명현영향，종이경조、경적겁지계동신경격소조체치료。
Objective:To analyse the influence of Shen-fu injection on fosinopril dose in patients with chronic cardiac failure of coronary heart disease. Methods:The patients with chronic cardiac failure of coronary heart disease in acute attack were been as research object,and were divided into two groups;one was Shen-fu treatment group(n=26)and the other was control group(n=23). Recorded fosinopril dose,mean arterial blood pressure,serum creatinine and blood urea nitrogen in two groups;and analysed the influence of Shen-fu injection on the application of fosinopril. Results:Fosinopril dose in Shen-fu treatment group was obviously higher than that in control group(P<0. 05). While there was no significant difference in two groups,such as mean arterial blood pressure, serum creatinine and blood urea nitrogen( P > 0. 05 ). Conclusion:The application of Shen - fu injection can remarkably increase fosinopril dose in patients with chronic cardiac failure of coronary heart disease in acute attack,and there is no obvious effect on blood pressure and renal function. Thus,the neurohormone interdict treatment can be applied more early and positively.