CAJ | 학술논문

目的：采用响应面法优化续断中川续断皂苷VI的提取工艺参数。方法：在单因素试验的基础上，利用Box-Benhnken中心组合设计，以川续断皂苷VI转移率为评价指标，考察超声时间、乙醇浓度、液料比3个因素的影响。结果：根据回归方程确定最佳提取工艺条件为：超声时间33.13 min ，乙醇浓度51.58%，液料比23.39 mL·g-1。采用该工艺条件得到的川续断皂苷VI的平均转移率为88.39%依0.212%（n越3），与理论预测值基本一致。结论：响应面模型与实际情况拟合良好，能较好地预测续断中川续断皂苷VI的转移率，该方法具有一定的实用价值。
목적：채용향응면법우화속단중천속단조감VI적제취공예삼수。방법：재단인소시험적기출상，이용Box-Benhnken중심조합설계，이천속단조감VI전이솔위평개지표，고찰초성시간、을순농도、액료비3개인소적영향。결과：근거회귀방정학정최가제취공예조건위：초성시간33.13 min ，을순농도51.58%，액료비23.39 mL·g-1。채용해공예조건득도적천속단조감VI적평균전이솔위88.39%의0.212%（n월3），여이론예측치기본일치。결론：향응면모형여실제정황의합량호，능교호지예측속단중천속단조감VI적전이솔，해방법구유일정적실용개치。
This study was aimed to optimize extraction technology of Asperosaponin VI from Dipsaci Radix by re-sponse surface methodology (RSM). A single-factor test and Box-Behnken design (BBD) were employed to optimize three extraction variables, including extraction time (A), ethanol concentration (B), and the ratio of ethanol to materi-al (C). The transfer rate of Asperosaponin VI was used as the evaluation index. The results showed that the optimized conditions were A of 33.13 min, B of 51.58 %, C of 23.39 mL·g-1. Under these conditions, the transfer rate was 88.39 ± 0.212% (n = 3), which was well matched with the predicted transfer rate. It was concluded that RSM can be used for extraction optimization of ultrasonic extraction process for Asperosaponin VI. This method had certain prac-tical values.