CAJ | 학술논문

目的：探讨血清降钙素原（procalcitonin，PCT）和C-反应蛋白（C-reactive protein，CRP）在恶性肿瘤合并感染的早期诊断价值。方法分别测定50例肿瘤患者合并感染前后、50例肿瘤非感染患者的PCT、CRP浓度，并进行统计分析。结果肿瘤患者合并感染后血清PCT和CRP水平明显高于感染前（P<0.01），也明显高于对照组（P<0.01）。肿瘤合并感染组的PCT升高的阳性率及CRP升高的阳性率两两比较无明显差异（P>0.05）。肿瘤合并感染组检测PCT与CRP呈正相关（r=0.726， P<0.01）。结论 PCT和CRP均可作为早期明确恶性肿瘤合并感染及其严重性的重要指标，在晚期肿瘤患者合并感染的诊断时均具有重要的意义，并可指导肿瘤患者合并感染时积极抗炎治疗。
목적：탐토혈청강개소원（procalcitonin，PCT）화C-반응단백（C-reactive protein，CRP）재악성종류합병감염적조기진단개치。방법분별측정50례종류환자합병감염전후、50례종류비감염환자적PCT、CRP농도，병진행통계분석。결과종류환자합병감염후혈청PCT화CRP수평명현고우감염전（P<0.01），야명현고우대조조（P<0.01）。종류합병감염조적PCT승고적양성솔급CRP승고적양성솔량량비교무명현차이（P>0.05）。종류합병감염조검측PCT여CRP정정상관（r=0.726， P<0.01）。결론 PCT화CRP균가작위조기명학악성종류합병감염급기엄중성적중요지표，재만기종류환자합병감염적진단시균구유중요적의의，병가지도종류환자합병감염시적겁항염치료。
Objective To investigate the clinical value of serum procalcitonin(PCT) and C-reactive protein(CRP) in early diagnosis of infection in the patients with malignant tumor.Methods The serum leval of PCT and CRP of 50 malignant tumor patients with local infection and 50 uninfection cases were measured and statistic analyzed.Results Serum leval of PCT and CRP of 50 malignant tumor patients with infection group was significantly elevated.(P<0.01). There was no significant difference between PCT and CRP of malignant tumor with infection. PCT has a positive relationship with CRP(r=0.726,P<0.01).Conclusion Combination of PCT and CRP was useful to early diagnosis and timely treatment of infection with malignant tumor.