中华老年多器官疾病杂志
中華老年多器官疾病雜誌
중화노년다기관질병잡지
CHINESE JOURNAL OF MULTIPLE ORGAN DISEASES IN THE ELDERLY
2014年
9期
648-651
,共4页
心力衰竭%交感神经激活%肾脏去神经术%能量代谢重构%高血压,肺性%心室动脉偶联
心力衰竭%交感神經激活%腎髒去神經術%能量代謝重構%高血壓,肺性%心室動脈偶聯
심력쇠갈%교감신경격활%신장거신경술%능량대사중구%고혈압,폐성%심실동맥우련
heart failure%sympathetic activation%renal denervation%energy metabolic remodeling%hypertension,pulmonary%ventricular-arterial coupling
心力衰竭（简称心衰）是老年人群中最常见的心血管疾病之一。本文综述了老年人心衰病理生理机制的特点；评价了交感神经过度激活、能量代谢重构在心衰中的作用及肾脏去神经术或曲美他嗪、辅酶Q10等药物治疗措施的疗效；同时介绍了肺动脉高压、心室-动脉偶联僵硬、系统性炎症状态等机制在射血分数保留心衰发生发展中的作用。
心力衰竭（簡稱心衰）是老年人群中最常見的心血管疾病之一。本文綜述瞭老年人心衰病理生理機製的特點；評價瞭交感神經過度激活、能量代謝重構在心衰中的作用及腎髒去神經術或麯美他嗪、輔酶Q10等藥物治療措施的療效；同時介紹瞭肺動脈高壓、心室-動脈偶聯僵硬、繫統性炎癥狀態等機製在射血分數保留心衰髮生髮展中的作用。
심력쇠갈（간칭심쇠）시노년인군중최상견적심혈관질병지일。본문종술료노년인심쇠병리생리궤제적특점；평개료교감신경과도격활、능량대사중구재심쇠중적작용급신장거신경술혹곡미타진、보매Q10등약물치료조시적료효；동시개소료폐동맥고압、심실-동맥우련강경、계통성염증상태등궤제재사혈분수보류심쇠발생발전중적작용。
Heart failure (HF) is one of the most common cardiovascular diseases in the elderly. The article reviewed the pathophysiological mechanisms of HF in the elderly, revealed the roles of excessive sympathetic activation and energy metabolic remodeling in the development of HF, and evaluated the efficacy of renal denervation, and drugs such as trimetazidine and coenzyme Q10. Meanwhile, we also introduced the roles of pulmonary artery hypertension, ventricular-arterial coupling stiffness and systemic inflammation in the development and progress of HF with preserved ejection fraction.
