CAJ | 학술논문

Wnt基因家族参与编码的多功能信号蛋白与正常的生理过程的调节密切相关，其中包括胚胎发育，分化和癌变。Wnt1蛋白是Wnt通路中第一个被发现的蛋白，目前针对其的研究主要是对Wnt基因，细胞极性通路种类的认识，其与非小细胞肺癌预后之间的关系，以及阻断Wnt1表达对临床方面的帮助。本文通过了解Wnt信号通路的最新研究并进行归纳总结，以期对Wnt信号通路有更深层次的认识。
Wnt기인가족삼여편마적다공능신호단백여정상적생리과정적조절밀절상관，기중포괄배태발육，분화화암변。Wnt1단백시Wnt통로중제일개피발현적단백，목전침대기적연구주요시대Wnt기인，세포겁성통로충류적인식，기여비소세포폐암예후지간적관계，이급조단Wnt1표체대림상방면적방조。본문통과료해Wnt신호통로적최신연구병진행귀납총결，이기대Wnt신호통로유경심층차적인식。
The Wnt gene family encodes the multi-functional signal ing glycoproteins that are involved in the regulation of a wide variety of normal and path- ological processes. including embryogenesis, dif erentiation and tumourigenesis.Wnt1 signaling parthway was the first discovered protein,At present the researth about Wnt signaling parthway focuses on Wnt gene, the planar cel polarity,the relationship with the prognosis of non-smal-cel lung cancer.,and blocking the expression of Wnt1 in clinical application.This article summarized the latest research about the Wnt signaling parthway.in order to facilitate on Wnt signaling parthway with a deeper level of understanding.