现代诊断与治疗
現代診斷與治療
현대진단여치료
MODERN DIAGNOSIS AND TREATMENT
2013年
15期
3363-3364
,共2页
低促性腺激素性性腺功能减退症%胰岛功能
低促性腺激素性性腺功能減退癥%胰島功能
저촉성선격소성성선공능감퇴증%이도공능
Idiopathic hypogonadotropic hypogonadism(IHH)%Islets function
目的:总结评价低促性腺激素性性腺功能减退症患者的胰岛功能。方法选取2009年11月~2010年9月期间我院收治的10例低促性腺激素性性腺功能减退症患者(IHH组)和10例正常体检者(对照组)为研究对象,分析比较性激素与胰岛功能之间的关系。结果 IHH组患者T、FSH、LH水平明显低于对照组,且差异具有统计学意义(P<0.05);IHH组空腹胰岛素、餐后2h胰岛素、HOMA-IR、HOMA-β等指标明显高于对照组,且差异具有统计学意义(P<0.05);性激素与胰岛功能呈负相关性。结论 IHH患者胰岛素水平高于正常人,且性激素越低者胰岛素水平越高。
目的:總結評價低促性腺激素性性腺功能減退癥患者的胰島功能。方法選取2009年11月~2010年9月期間我院收治的10例低促性腺激素性性腺功能減退癥患者(IHH組)和10例正常體檢者(對照組)為研究對象,分析比較性激素與胰島功能之間的關繫。結果 IHH組患者T、FSH、LH水平明顯低于對照組,且差異具有統計學意義(P<0.05);IHH組空腹胰島素、餐後2h胰島素、HOMA-IR、HOMA-β等指標明顯高于對照組,且差異具有統計學意義(P<0.05);性激素與胰島功能呈負相關性。結論 IHH患者胰島素水平高于正常人,且性激素越低者胰島素水平越高。
목적:총결평개저촉성선격소성성선공능감퇴증환자적이도공능。방법선취2009년11월~2010년9월기간아원수치적10례저촉성선격소성성선공능감퇴증환자(IHH조)화10례정상체검자(대조조)위연구대상,분석비교성격소여이도공능지간적관계。결과 IHH조환자T、FSH、LH수평명현저우대조조,차차이구유통계학의의(P<0.05);IHH조공복이도소、찬후2h이도소、HOMA-IR、HOMA-β등지표명현고우대조조,차차이구유통계학의의(P<0.05);성격소여이도공능정부상관성。결론 IHH환자이도소수평고우정상인,차성격소월저자이도소수평월고。
Objective To investigate islets function in patients with idiopathic hypogonadotropic hy-pogonadism (IHH). Methods 10 patients in IHH and 10 normal volunteers in our hospital from November 2009 to September 2010 were included into our study. The relationship between sex hormones and islets function was analyzed. Results T, FSH, LH levels of IHH patients were sig-nificantly lower than those of the control group. The difference was statistically significant(P<0.05). The fasting insulin , 2h postprandial insulin, HOMA-IR and HOMA-β of IHH group were signifi-cantly higher than those of the control group, and the difference was statistically significant (P<0.05). Sex hormones and islets function was negatively correlated (P<0.05). Conclusion TThe in-sulin levels of IHH patients are higher than those of normal subjects. The sex hormones and islets function are negatively correlated in IHH patients.