CAJ | 학술논문

目的：了解我院抗菌药物应用情况及趋势。方法统计、分析2009~2011年各类抗菌药物销售金额、用药频度(DDDS)。结果抗菌药物销售金额在逐年增加，但抗菌药物销售金额占药品总销售金额的比例在2011年大幅下降；头孢菌素类销售金额均占抗菌药物销售金额的55%以上，头孢菌素类及青霉类的DDDS排序一直居前三位。结论我院使用最多的抗菌药物是头孢菌素类、青霉素类、碳青霉烯和其他β-内酰胺类，不合理使用抗菌药物的现象正在改观，需进一步加强抗菌药物临床应用管理，促进合理使用。
목적：료해아원항균약물응용정황급추세。방법통계、분석2009~2011년각류항균약물소수금액、용약빈도(DDDS)。결과항균약물소수금액재축년증가，단항균약물소수금액점약품총소수금액적비례재2011년대폭하강；두포균소류소수금액균점항균약물소수금액적55%이상，두포균소류급청매류적DDDS배서일직거전삼위。결론아원사용최다적항균약물시두포균소류、청매소류、탄청매희화기타β-내선알류，불합리사용항균약물적현상정재개관，수진일보가강항균약물림상응용관리，촉진합리사용。
Objective To understand the application and trend of the antibacterials in our hospital. Methods To gather statistics and analyze the amount of sales and the frequence of drug use (DDDS) of all kinds of the antibacterials from 2009 to 2011. Results The amount of sales of the antibacterials have increased year by year, but the proportion in the total amount of sales of drugs declined sharply in 2011. The amount of sales of the cephalosporines accounted for more than 50%of the amount of sales of the antibacterials. The DDDS of the cephalosporines and the penicillines have been in the top three. Conclusion The cephalosporines, the penicillines, the carbapenems and otherβ-Lactams were used at most in our hospital, and the unreasonable application has been changed. The management of the clinical application of the antibacterials needs further strengthening to promote the rational use.