中国循环杂志
中國循環雜誌
중국순배잡지
CHINESE CIRCULATION JOURNAL
2014年
9期
694-697
,共4页
急性缺血性脑卒中%复发%危险因素%预测价值
急性缺血性腦卒中%複髮%危險因素%預測價值
급성결혈성뇌졸중%복발%위험인소%예측개치
Acute ischemic stroke%Recurrence%Risk factor%Predictive value
目的：探讨急性缺血性脑卒中复发危险因素，并分析低密度脂蛋白（LDL）/高密度脂蛋白（HDL）的预测价值。<br> 方法：对我院收治的143例急性缺血性脑卒中患者进行为期2年的随访，探讨患者复发的危险因素以及LDL/HDL与脑卒中复发的相关性，分析LDL/HDL在脑卒中复发中的预测价值。<br> 结果：单因素分析显示，腔隙性脑梗死、有无合并高血压、血压、LDL、HDL、LDL/HDL、甘油三酯（TG）水平，以及脑卒中量表评分和生活能力评分是导致缺血性脑卒中复发的危险因素；多因素分析显示合并高血压、LDL/HDL、TG水平是导致缺血性脑卒中复发的独立危险因素。LDL、LDL/HDL与脑卒中复发呈明显正相关关系，HDL水平与脑卒中复发呈负相关（P<0.05）；LDL/HDL检测对脑卒中复发的特异性和敏感性分别为81.16%和95.65%，均显著高于两种指标单独检测。<br> 结论：LDL/HDL预测缺血性脑卒中复发的作用有利于我们识别缺血性脑卒中复发的高危患者，有利于临床进行早期的干预和预防。
目的：探討急性缺血性腦卒中複髮危險因素，併分析低密度脂蛋白（LDL）/高密度脂蛋白（HDL）的預測價值。<br> 方法：對我院收治的143例急性缺血性腦卒中患者進行為期2年的隨訪，探討患者複髮的危險因素以及LDL/HDL與腦卒中複髮的相關性，分析LDL/HDL在腦卒中複髮中的預測價值。<br> 結果：單因素分析顯示，腔隙性腦梗死、有無閤併高血壓、血壓、LDL、HDL、LDL/HDL、甘油三酯（TG）水平，以及腦卒中量錶評分和生活能力評分是導緻缺血性腦卒中複髮的危險因素；多因素分析顯示閤併高血壓、LDL/HDL、TG水平是導緻缺血性腦卒中複髮的獨立危險因素。LDL、LDL/HDL與腦卒中複髮呈明顯正相關關繫，HDL水平與腦卒中複髮呈負相關（P<0.05）；LDL/HDL檢測對腦卒中複髮的特異性和敏感性分彆為81.16%和95.65%，均顯著高于兩種指標單獨檢測。<br> 結論：LDL/HDL預測缺血性腦卒中複髮的作用有利于我們識彆缺血性腦卒中複髮的高危患者，有利于臨床進行早期的榦預和預防。
목적：탐토급성결혈성뇌졸중복발위험인소，병분석저밀도지단백（LDL）/고밀도지단백（HDL）적예측개치。<br> 방법：대아원수치적143례급성결혈성뇌졸중환자진행위기2년적수방，탐토환자복발적위험인소이급LDL/HDL여뇌졸중복발적상관성，분석LDL/HDL재뇌졸중복발중적예측개치。<br> 결과：단인소분석현시，강극성뇌경사、유무합병고혈압、혈압、LDL、HDL、LDL/HDL、감유삼지（TG）수평，이급뇌졸중량표평분화생활능력평분시도치결혈성뇌졸중복발적위험인소；다인소분석현시합병고혈압、LDL/HDL、TG수평시도치결혈성뇌졸중복발적독립위험인소。LDL、LDL/HDL여뇌졸중복발정명현정상관관계，HDL수평여뇌졸중복발정부상관（P<0.05）；LDL/HDL검측대뇌졸중복발적특이성화민감성분별위81.16%화95.65%，균현저고우량충지표단독검측。<br> 결론：LDL/HDL예측결혈성뇌졸중복발적작용유리우아문식별결혈성뇌졸중복발적고위환자，유리우림상진행조기적간예화예방。
Objective: To analyze the risk factors and the predictive value of LDL/HDL ratio in acute ischemic stroke recurrence. <br> Methods: A total of 143 patients with acute ischemic stroke treated in our hospital were studied. The patients were followed-up for 2 years, the risk factors and the predictive value of LDL/HDL ratio for stroke recurrence were analyzed. <br> Results: Single factor analysis indicated that lacunar infarction, hypertension, blood pressure, the levels of LDL, HDL, ratio of LDL/HDL, stroke scale score, life ability score were the risk factors of ischemic stroke recurrence. Multivariate analysis presented that hypertension, ratio of LDL/HDL, TG level were the independent risk factors for ischemic stroke recurrence. LDL and ratio of LDL/HDL were positively related to ischemic stroke recurrence, HDL was negatively related to ischemic stroke recurrence, P<0.05. The speciifcity and sensitivity of LDL/HDL for predicting ischemic stroke recurrence were at 81.16%and 95.65%respectively. <br> Conclusion: The predictive value of LDL/HDL ratio could help us to identify the patients with high risk of ischemic stroke recurrence which is important for the early clinical intervention.
