中国性科学
中國性科學
중국성과학
THE CHINESE JOURNAL OF HUMAN SEXUALITY
2014年
4期
10-13
,共4页
子宫内膜异位症%腹腔镜保守手术%曲普瑞林%疗效
子宮內膜異位癥%腹腔鏡保守手術%麯普瑞林%療效
자궁내막이위증%복강경보수수술%곡보서림%료효
Endometriosis%Laparoscopic surgery%Triptorelin%Curative effect
目的：探讨曲普瑞林联合腹腔镜保守手术治疗子宫内膜异位症的疗效观察。方法：82例子宫内膜异位症患者分为联合组与对照组。两组患者均予以腹腔镜保守手术治疗，联合组术后予以曲普瑞林3.75 mg肌注，每月1次，连用6个月。观察并比较两组患者治疗前后性激素水平的变化、治疗结束后随访6个月的治疗效果、1年内怀孕情况及不良反应情况。结果：治疗6个月后，两组患者性激素FSH、LH、E2水平均较治疗前下降（P＜0.05或P＜0.01），且联合组下降幅度明显优于对照组（P＜0.05）；治疗结束后随访6个月，联合组患者的临床疗效明显优于对照组，复发率明显低于对照组（χ2＝5.14，P＜0.05）；停药1年后，联合组患者的成功怀孕率明显高于对照组（χ2＝4.02，P＜0.05），两组患者治疗期间不良反应发生率比较无明显统计学差异（P＞0.05）。结论：曲普瑞林联合腹腔镜保守手术治疗子宫内膜异位症可以取得较单纯手术治疗更好的疗效，降低术后复发率，提高怀孕率，不良反应少。
目的：探討麯普瑞林聯閤腹腔鏡保守手術治療子宮內膜異位癥的療效觀察。方法：82例子宮內膜異位癥患者分為聯閤組與對照組。兩組患者均予以腹腔鏡保守手術治療，聯閤組術後予以麯普瑞林3.75 mg肌註，每月1次，連用6箇月。觀察併比較兩組患者治療前後性激素水平的變化、治療結束後隨訪6箇月的治療效果、1年內懷孕情況及不良反應情況。結果：治療6箇月後，兩組患者性激素FSH、LH、E2水平均較治療前下降（P＜0.05或P＜0.01），且聯閤組下降幅度明顯優于對照組（P＜0.05）；治療結束後隨訪6箇月，聯閤組患者的臨床療效明顯優于對照組，複髮率明顯低于對照組（χ2＝5.14，P＜0.05）；停藥1年後，聯閤組患者的成功懷孕率明顯高于對照組（χ2＝4.02，P＜0.05），兩組患者治療期間不良反應髮生率比較無明顯統計學差異（P＞0.05）。結論：麯普瑞林聯閤腹腔鏡保守手術治療子宮內膜異位癥可以取得較單純手術治療更好的療效，降低術後複髮率，提高懷孕率，不良反應少。
목적：탐토곡보서림연합복강경보수수술치료자궁내막이위증적료효관찰。방법：82례자궁내막이위증환자분위연합조여대조조。량조환자균여이복강경보수수술치료，연합조술후여이곡보서림3.75 mg기주，매월1차，련용6개월。관찰병비교량조환자치료전후성격소수평적변화、치료결속후수방6개월적치료효과、1년내부잉정황급불량반응정황。결과：치료6개월후，량조환자성격소FSH、LH、E2수평균교치료전하강（P＜0.05혹P＜0.01），차연합조하강폭도명현우우대조조（P＜0.05）；치료결속후수방6개월，연합조환자적림상료효명현우우대조조，복발솔명현저우대조조（χ2＝5.14，P＜0.05）；정약1년후，연합조환자적성공부잉솔명현고우대조조（χ2＝4.02，P＜0.05），량조환자치료기간불량반응발생솔비교무명현통계학차이（P＞0.05）。결론：곡보서림연합복강경보수수술치료자궁내막이위증가이취득교단순수술치료경호적료효，강저술후복발솔，제고부잉솔，불량반응소。
Objectives:To discuss the curative effect of Triptorelin combined with laparoscopic surgery in the treatment of endometriosis.Method:82 patients with endometriosis were randomly divided into the treatment group and the control group.The patients in 2 group were both given the laparoscopic surgery,while the patients in the treatment group were additionally given 3.75mg Triptorelin intramuscular injection once a month for 6 months. The changes of sex hormone levels of patients in two groups were observed and compared before and after treatment. Results:The 6 hormone (FSH,LH,E2)levels of patients in 2 groups declined six months after treatment (P<0. 05 or P<0.01),and the declining rate in the treatment group was much better than that in the control group (P<0.05).As for the 6 months’follow-up after the treatment,the curative effect of the treatment group was much better than that of the control group,and the reoccurrence rate was much lower than that of the control group (χ2 =5.14,P<0.05).After one year’s drug withdrawal,the successful pregnancy rate of patients in the treatment group was much higher than that in the control group (χ2 =4.02,P<0.05 ).After comparing the untoward effect rates of patients in 2 groups during treatment,there was no significant statistical difference (P>0.05 ).Conclusion:Triptorelin combined with laparoscopic surgery has reliable effect on endometriosis,which can reduce the postopera-tive reoccurrence rate and increase the pregnancy rate with less untoward effect.
