CAJ | 학술논문

目的探讨腹膜透析相关性真菌性腹膜炎(PDFP)的易感因素、诊治和预后,以提高真菌性腹膜炎的诊治水平.方法回顾性分析惠州市中心人民医院腹膜透析中心2005年1月至2013年8月25例PDFP病例,分析患者的临床资料、病原体、治疗、预后.结果 PDFP占腹膜透析相关性腹膜炎的比例是7.89％; PDFP发生前4周使用过抗生素13例(52％);14例(56％)拔管后改为长期血液透析,死亡11例(44％);死亡组与存活组在糖尿病、血液透析、10d内拔管方面差异有统计学意义(P＜0.05).结论使用抗生素是PDFP发生的危险因素,PDFP预后不良,确诊后早期拔管可降低死亡率.糖尿病、血液透析、10d内拔管是影响患者预后的因素.
목적 탐토복막투석상관성진균성복막염(PDFP)적역감인소、진치화예후,이제고진균성복막염적진치수평.방법 회고성분석혜주시중심인민의원복막투석중심2005년1월지2013년8월25례PDFP병례,분석환자적림상자료、병원체、치료、예후.결과 PDFP점복막투석상관성복막염적비례시7.89％; PDFP발생전4주사용과항생소13례(52％);14례(56％)발관후개위장기혈액투석,사망11례(44％);사망조여존활조재당뇨병、혈액투석、10d내발관방면차이유통계학의의(P＜0.05).결론 사용항생소시PDFP발생적위험인소,PDFP예후불량,학진후조기발관가강저사망솔.당뇨병、혈액투석、10d내발관시영향환자예후적인소.
Objective To investigate risk factors,diagnosis,treatment and prognosis of peritoneal dialysis-related fungal peritonitis (PDFP),and to improve the level of the diagnosis and treatment of fungal peritonitis.Methods We retrospectively reviewed 25 cases of PDFP in our hospital from January 2005 to August 2013,the clinical data,pathogens,treatment and prognosis of patients were analyzed.Results PDFP patients accounted for the proportion of patients with peritoneal dialysis related peritonitis was 7.89％.13 cases (52％) had a history of antibiotic use within 4 weeks before PDFP.14 cases (56％) withdrew peritoneal dialysis to hemodialysis,11 cases (44％) died.Diabetes,hemodialysis and catheter removal showed statistical significant difference in survival and dead groups (P ＜ 0.05).Conclusion The risk factors for PDFP identified in this study was the use of antibiotics.PDFP has poor prognosis and higher mortality,early catheter removal can help to decrease the mortality.Diabetes,hemodialysis,and catheter removal were factors influencing the prognosis of patients.