CAJ | 학술논문

目的探讨血同型半胱氨酸(HCY)水平对急性心肌梗死(AMI)患者急诊经皮冠状动脉介入治疗（PCI）预后的影响。方法入选接受急诊PCI的AMI患者86例，根据血HCY水平分为高同型半胱氨酸血症（HHcy）组（37例）和对照组（49例），两组均给予PCI术后常规治疗，并进行为期6个月的术后随访，分析随访期间的主要心血管事件（MACE）与HCY水平的相关性。结果与对照组比较，HHcy组MACE发生率明显高于对照组，差异具有统计学意义(P=0.011)；结论血HCY水平与急诊PCI术后的MACE发生率密切相关，是其预后的独立预测因素。
목적탐토혈동형반광안산(HCY)수평대급성심기경사(AMI)환자급진경피관상동맥개입치료（PCI）예후적영향。방법입선접수급진PCI적AMI환자86례，근거혈HCY수평분위고동형반광안산혈증（HHcy）조（37례）화대조조（49례），량조균급여PCI술후상규치료，병진행위기6개월적술후수방，분석수방기간적주요심혈관사건（MACE）여HCY수평적상관성。결과여대조조비교，HHcy조MACE발생솔명현고우대조조，차이구유통계학의의(P=0.011)；결론혈HCY수평여급진PCI술후적MACE발생솔밀절상관，시기예후적독립예측인소。
Objective To investigate the effects of homocysteine (HCY) level in patients treated with emergency percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI). Methods 86 consequent AMI patients treated with emergency PCI were divided into HHCY group (n=37) and control group (n=49). and the maior adverse cardiac events (MACE) during at 6 months of follow-up were compared between the two groups and analyzed for their association with Hcy level. Results At 6 months of follow-up,tincidence of MACE of HHcy groups was significantly higher (P=0.011) than that of control groups. Conclu-sion Blood HCY levels are closely correlated with the incidence of MACE following emergency PCI ,and it may be the indepen-dent predictor factor for prognosis.