CAJ | 학술논문

目的：探讨高血压病中医证型、危险因素及2型糖尿病的关系，揭示高血压病中西医病因病机，为高血压病合并2型糖尿病的前期研究提供新的思路及依据。方法：选取高血压病患者400例，运用OGTT进行评定，按其是否合并2型糖尿病分为2组。同时重点询问病史(家族史、冠心病史、糖尿病史和脑卒中史)；测定身高(H)、体质量(W)；检测空腹血糖(FPG)、餐后2小时血糖(2 hPBG)，血脂四项总胆固醇(CHOL)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)以及尿酸(UA)，并进行血压测定。计算体重指数(BMI)=W(kg)/[H(m)]2。结果：①高血压合并2型糖尿病组中医证型以阴虚阳亢证多见，其次为痰湿壅盛、肝火亢盛、阴阳两虚。②高血压合并2型糖尿病组（A组）各指标相比较，A组患者家族史、冠心病史及收缩压明显高于高血压病不合并2型糖尿病组(B组)(P＜0.05）；B组患者BMI、TC、TG、FPG、2hPBG、HDL、LDL、UA与A组相比无显著性差异(P＞0.05)。结论：①A组患者中医证型以虚实夹杂为主，以阴虚阳亢证多见；②甘油三酯、BMI增高以及高血压家族史、冠心病史、收缩压高是高血压合并2型糖尿病的主要危险因素。
목적：탐토고혈압병중의증형、위험인소급2형당뇨병적관계，게시고혈압병중서의병인병궤，위고혈압병합병2형당뇨병적전기연구제공신적사로급의거。방법：선취고혈압병환자400례，운용OGTT진행평정，안기시부합병2형당뇨병분위2조。동시중점순문병사(가족사、관심병사、당뇨병사화뇌졸중사)；측정신고(H)、체질량(W)；검측공복혈당(FPG)、찬후2소시혈당(2 hPBG)，혈지사항총담고순(CHOL)、감유삼지(TG)、고밀도지단백(HDL)、저밀도지단백(LDL)이급뇨산(UA)，병진행혈압측정。계산체중지수(BMI)=W(kg)/[H(m)]2。결과：①고혈압합병2형당뇨병조중의증형이음허양항증다견，기차위담습옹성、간화항성、음양량허。②고혈압합병2형당뇨병조（A조）각지표상비교，A조환자가족사、관심병사급수축압명현고우고혈압병불합병2형당뇨병조(B조)(P＜0.05）；B조환자BMI、TC、TG、FPG、2hPBG、HDL、LDL、UA여A조상비무현저성차이(P＞0.05)。결론：①A조환자중의증형이허실협잡위주，이음허양항증다견；②감유삼지、BMI증고이급고혈압가족사、관심병사、수축압고시고혈압합병2형당뇨병적주요위험인소。
Objective:To provide new thinking and evidence for preliminary study of hypertension complicat-ed with type 2 diabetes mellitus (T2DM) by exploring the connections of hypertension TCM patterns and its risk fac-tors to T2DM, as well as revealing the etiology and pathogenesis of hypertension. Methods:Altogether 400 hyper-tension patients were judged by OGTT and separated into two groups according to whether they were complicated with T2DM. Meanwhile, medical history (family history, the history of coronary heart disease, diabetes mellitus and stroke) of all the patients was inquired; height (H) and body weight (W) were detected; fasting plasma glucose (FPG), 2h postprandial blood glucose (2hPBG), total cholesterol (CHOL), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL) and uric acid (UA) were measured, and blood pressure deteceted. Body weight was calculated (BMI)=W(kg)/[H(m)]2. Results:①Yin-deficiency and Yang-hyperactivity was the most com-mon TCM pattern in the patients suffering from hypertension complicated with T2DM, the next were accumulation of phlegm-damp, hyperactivity of liver-fire and dual deficiency of Yin-yang.②the complication (A) group was ob-viously higher than hypertension (B) group in family history, the history of coronary heart disease and systolic pres-sure;there was no significant difference when B group was compared with A group in BMI, TC, TG, FPG, 2hPBG, HDL, LDL and UA (P>0.05). Conclusion:①The patients suffering from hypertension complicated with T2DM is maily of intermingled deficiency-excess pattern, Yin-deficiency Yang-hyperactivity pattern could be seen most fre-quently;②The main risk factors of hypertension complicated with T2DM are TG, the increase of BMI, family his-tory of hypertension, the history of coronary heart disease and high systolic pressure.