CAJ | 학술논문

目的：探讨脊髓神经低强度刺激(LL-SCS)对心房神经节丛(GP)功能的影响。方法13只成年杂种犬随机分为两组：实验组7只，对T1~2)节段脊髓神经予以高频刺激并以引起肌肉震颤的最低电压强度为刺激阈值，使用90%的阈值强度进行LL-SCS刺激并持续6 h；对照组6只，在T1~2节段附近寻找一处体表皮肤予以同样6 h低强度刺激。分别在基础状态、3 h和6 h末测定递增电压刺激右前GP（ARGP）引起的心率变化。将刺激电压与心率变化的百分比分别作为横坐标和纵坐标绘制出ARGP的心率-电压反应曲线。结果对照组ARGP的心率-电压反应曲线没有显著性改变；实验组ARGP的心率-电压反应曲线逐渐被钝化，而且相同电压引起的心率降低的百分比显著性逐渐降低。结论 LL-SCS可以明显抑制ARGP的功能。
목적：탐토척수신경저강도자격(LL-SCS)대심방신경절총(GP)공능적영향。방법13지성년잡충견수궤분위량조：실험조7지，대T1~2)절단척수신경여이고빈자격병이인기기육진전적최저전압강도위자격역치，사용90%적역치강도진행LL-SCS자격병지속6 h；대조조6지，재T1~2절단부근심조일처체표피부여이동양6 h저강도자격。분별재기출상태、3 h화6 h말측정체증전압자격우전GP（ARGP）인기적심솔변화。장자격전압여심솔변화적백분비분별작위횡좌표화종좌표회제출ARGP적심솔-전압반응곡선。결과대조조ARGP적심솔-전압반응곡선몰유현저성개변；실험조ARGP적심솔-전압반응곡선축점피둔화，이차상동전압인기적심솔강저적백분비현저성축점강저。결론 LL-SCS가이명현억제ARGP적공능。
Objective To investigate the effects of low-level T1~2 spinal cord stimulation (SCS) on the func-tion of atrial ganglinated plexi. Methods Thirteen adult dogs were randomly divided into two groups. In the experi-mental group (n=7), the dogs were given 90% high frequency stimulation at the minimum voltage which can cause muscle tremors for six hours on the T1~2 spinal cord. In the control group (n=7), the dogs were given the same stimula-tion on the skin which was near to T1~2 spinal cord. The heart rate (HR) changes induced by the voltages stimulation of ARGP at baseline 3 h and 6 h were measured. Then the voltage response curves which represented the function status of ARGP were made in which the abscissa denoted the stimulating voltages and the ordinate denoted the maximal HR changes. Results In the control group, there was no distinct change on the HR-Voltage curve of ARGP. While in the experimental group, the HR-Voltage of ARGP was gradually passivated, and the maximal HR changes decreased by the same voltages. Conclusion LL-SCS can inhibit the function of ARGP.