CAJ | 학술논문

目的：分析重庆某地戊型肝炎的临床特点及预后，为临床防治提供参考。方法回顾性分析重庆市大足区人民医院2005～2013年收治的140例戊型肝炎患者临床特点，并根据性别和年龄进行分组，比较实验室检查结果。结果食欲缺乏、乏力为戊型肝炎患者主要临床表现。戊型肝炎患者中，男性患者发生率高于女性患者，其中又以老年男性患者所占比率最大（54．3％）。男女两组间总胆红素、直接胆红素比较，差异有统计学意义（ P＜0．05）。男性中老年组与男性青年组总胆红素、清蛋白、凝血酶原活动度比较，差异有统计学意义（P＜0．05），女性中老年组与女性青年组总胆红素、直接胆红素比较，差异也有统计学意义（P＜0．05）。结论戊型肝炎患者男性患者比率高于女性，临床表现较女性患者严重。中老年男性患者由于受到性别、年龄双重因素的影响，临床表现最重，易发展为重型肝炎，预后较差。
목적：분석중경모지무형간염적림상특점급예후，위림상방치제공삼고。방법회고성분석중경시대족구인민의원2005～2013년수치적140례무형간염환자림상특점，병근거성별화년령진행분조，비교실험실검사결과。결과식욕결핍、핍력위무형간염환자주요림상표현。무형간염환자중，남성환자발생솔고우녀성환자，기중우이노년남성환자소점비솔최대（54．3％）。남녀량조간총담홍소、직접담홍소비교，차이유통계학의의（ P＜0．05）。남성중노년조여남성청년조총담홍소、청단백、응혈매원활동도비교，차이유통계학의의（P＜0．05），녀성중노년조여녀성청년조총담홍소、직접담홍소비교，차이야유통계학의의（P＜0．05）。결론무형간염환자남성환자비솔고우녀성，림상표현교녀성환자엄중。중노년남성환자유우수도성별、년령쌍중인소적영향，림상표현최중，역발전위중형간염，예후교차。
Objective To analyze the features and prognosis of Hepatitis E in Dazu area of Chongqing .Meth-ods Data of one hundred and forty patients with Hepatitis from 2005 to 2013 were analyzed retrospectively .Accord-ing to different sex and age ,140 patients were divided into different groups ,and laboratory test results were compared among these groups .Results Anorexia and fatigue were main clinical manifestations of Hepatitis E .The rate of in-fecting with Hepatitis E in males was higher than that in females ,that of middle and old males was significant higher than others .The levels of total bilirubin and direct bilirubin were significant different between the males and females (P<0 .05) .The differences of total bilirubin ,direct bilirubin ,albumin and prothrombin activity were significant be-tween the middle ,old male group and young male group ,the differences also showed in females(P<0 .05) .Conclusion The rate of infecting with Hepatitis E in males was higher than that in females ,and the symptoms of male was seve-rer than female .because the double effect of sex and age ,the middle and old male patients had sever symptoms and easily changed into sever Hepatitis ,had a poor prognosis .