CAJ | 학술논문

目的：探讨女性绝经年限与代谢综合征（M S ）的关系。方法选取重庆城市地区40岁以上女性为调查人群，对所有受试者进行问卷调查、体格检查，同时检测生化指标，最终有1402名自然绝经的女性纳入该研究。将研究对象按绝经年限小于5年、5～＜10年、10～＜15年、≥15年分组，采用Logistic回归分析绝经年限与MS及其组分的关系。结果该研究人群MS患病率为40．87％，患MS的女性绝经年限明显高于非MS者（P＜0．05）。绝经后女性MS患病率在绝经年限小于5年、5～＜10年、10～＜15年、≥15年分别为29．37％、34．29％、45．30％、49．13％（ P＜0．05）。校正年龄、BM I后（除中心性肥胖），绝经年限在10～＜15年组的M S的患病风险是绝经年限小于5年的1．54倍。当绝经年限大于或等于15年时，该风险进一步上升至1．71倍。Logistic回归分析显示，BMI及绝经年限是MS的影响因素。结论绝经后女性是MS的高危人群，且绝经年限与MS相关。
목적：탐토녀성절경년한여대사종합정（M S ）적관계。방법선취중경성시지구40세이상녀성위조사인군，대소유수시자진행문권조사、체격검사，동시검측생화지표，최종유1402명자연절경적녀성납입해연구。장연구대상안절경년한소우5년、5～＜10년、10～＜15년、≥15년분조，채용Logistic회귀분석절경년한여MS급기조분적관계。결과해연구인군MS환병솔위40．87％，환MS적녀성절경년한명현고우비MS자（P＜0．05）。절경후녀성MS환병솔재절경년한소우5년、5～＜10년、10～＜15년、≥15년분별위29．37％、34．29％、45．30％、49．13％（ P＜0．05）。교정년령、BM I후（제중심성비반），절경년한재10～＜15년조적M S적환병풍험시절경년한소우5년적1．54배。당절경년한대우혹등우15년시，해풍험진일보상승지1．71배。Logistic회귀분석현시，BMI급절경년한시MS적영향인소。결론절경후녀성시MS적고위인군，차절경년한여MS상관。
Objective To explore the relationship between the women menopausal period and metabolic syndrome (MS) .Meth-ods The female residents of Chongqing urban areas above 40 years were selected as the investigation group ,all the subjects were performed the questionnaire survey and the physical examination ,at the same time the biochemical indexes were detected .Finally , 1402 women of natural menopause were included in this study .The study subjects were divided into different groups according to the menopausal period of <5 years ,5- <10 years ,10- <15 years and ≥15 years .The Logistic regression analysis was adopted to analyze the relationship between the menopausal period with MS and its components .Results The MS prevalence in this group was 40 .87% ,and the menopausal period of the women with MS was significantly higher than that without MS (P<0 .05) .The MS prevalences of postmenopausal women in the menopause period of <5 years ,5 - <10 years ,10 - <15 years and ≥15 years were 29 .37% ,34 .29% ,45 .30% and 49 .13% respectively (P<0 .05) .After adjustment for age and BMI (except central obesity ) ,the MS risk in the menopausal period of 10- <15 years and was 1 .54 times of that in the menopausal period of <5 years .The Logis-tic regression analysis showed that BMI and menopausal period were the influence factors of MS .Conclusion Post-menopausal women are the high-risk group of MS and the menopausal period is correlated to MS .