重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2014年
26期
3427-3430
,共4页
乳腺肿瘤%前哨淋巴结活组织检查%假阴性反应%核素%亚甲蓝
乳腺腫瘤%前哨淋巴結活組織檢查%假陰性反應%覈素%亞甲藍
유선종류%전초림파결활조직검사%가음성반응%핵소%아갑람
breast neoplasms%sentinel lymph node biopsy%false negative reactions%isotope%methylene blue
目的：通过严格的筛查条件对早期乳腺癌行前哨淋巴结活检（SLNB），分析前哨淋巴结（SLN）对腋窝淋巴结状态预测的准确性。方法联合核素和亚甲蓝对266例全程在该科治疗的早期乳腺癌行SLNB ，然后行常规腋窝淋巴结清扫，以病理检查为标准了解影响SLNB的相关因素。结果 SLN检出率100％，准确率98．50％，假阴性率4．44％，灵敏度95．56％；SLN的准确率与肿块大小、病理类型及腋窝淋巴结情况有相关性（P＜0．01）；SLN的假阴性率和肿块的位置相关（P＜0．05）。结论核素联合亚甲蓝在早期乳腺癌患者中行SLNB是可行的，SLNB可准确预测腋窝淋巴结的转移状态。
目的：通過嚴格的篩查條件對早期乳腺癌行前哨淋巴結活檢（SLNB），分析前哨淋巴結（SLN）對腋窩淋巴結狀態預測的準確性。方法聯閤覈素和亞甲藍對266例全程在該科治療的早期乳腺癌行SLNB ，然後行常規腋窩淋巴結清掃，以病理檢查為標準瞭解影響SLNB的相關因素。結果 SLN檢齣率100％，準確率98．50％，假陰性率4．44％，靈敏度95．56％；SLN的準確率與腫塊大小、病理類型及腋窩淋巴結情況有相關性（P＜0．01）；SLN的假陰性率和腫塊的位置相關（P＜0．05）。結論覈素聯閤亞甲藍在早期乳腺癌患者中行SLNB是可行的，SLNB可準確預測腋窩淋巴結的轉移狀態。
목적：통과엄격적사사조건대조기유선암행전초림파결활검（SLNB），분석전초림파결（SLN）대액와림파결상태예측적준학성。방법연합핵소화아갑람대266례전정재해과치료적조기유선암행SLNB ，연후행상규액와림파결청소，이병리검사위표준료해영향SLNB적상관인소。결과 SLN검출솔100％，준학솔98．50％，가음성솔4．44％，령민도95．56％；SLN적준학솔여종괴대소、병리류형급액와림파결정황유상관성（P＜0．01）；SLN적가음성솔화종괴적위치상관（P＜0．05）。결론핵소연합아갑람재조기유선암환자중행SLNB시가행적，SLNB가준학예측액와림파결적전이상태。
Objective To perform the sentinel lymph node biopsy (SLNB) in the patients with early breast cancer by the strict screening conditions and to analyze the accuracy of the sentinel lymph node for predicting the axillary lymph node status .Methods SLNB combined with methylene blue dye and isotope was performed in 266 cases of early breast cancer treated in this department with full treatment courses .Then the axillary lymph node dissection(ALND) was routinely conducted .With the pathological ex-amination as the standard ,the related factors affecting SLNB were analyzed .Results The detection rate of SLN ,accuracy rate ,sen-sitivity and the false negative rate were 100% ,98 .5% ,95 .56% and 4 .44% respectively ;the accuracy of SLN was significantly cor-related with the tumor size ,pathological type and axillary lymph node status(P<0 .01);the false negative rate of SLN was related with the tumor location(P<0 .05) .Conclusion The combination of methylene blue dye and isotope used in SLNB is feasible in the patients with early breast cancer ,SLN could accurately predict the axillary lymph node metastasis status .
