中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
27期
141-143
,共3页
胎盘蛋白13%子痫前期孕妇%妊娠中晚期
胎盤蛋白13%子癇前期孕婦%妊娠中晚期
태반단백13%자간전기잉부%임신중만기
Placental protein 13%Preeclampsia pregnant women%Early to late pregnancy
目的：研究探讨妊娠子痫前期患者血清中的胎盘蛋白13（PP13）含量与孕妇妊娠孕周长短的变化关系。方法：回顾性分析本院收治的44例子痫前期患者的临床资料。将其分为轻度子痫前期组16例和重度子痫前期组28例；另外选择30例正常健康孕妇设为对照组。采用ELISA检测方法测定孕妇在不同孕周时血清中的PP13的含量。结果：轻、重度子痫前期组血清中PP13的含量均显著高于正常孕妇组（P<0.05）；且重度子痫前期组显著高于轻度子痫前期组（P<0.05）；各组妊娠晚期血清中PP13的含量显著高于妊娠中期（P<0.05）；相对于妊娠中期，子痫前期组妊娠晚期孕妇血清中PP13含量的增加值显著高于正常孕妇组（P<0.05）。结论：重度子痫前期孕妇血清中的PP13的含量高于轻度子痫前期孕妇，子痫前期患者血清中的PP13的含量高于正常孕妇，随着妊娠时间的延长，孕妇血清内PP13的含量有所增高。
目的：研究探討妊娠子癇前期患者血清中的胎盤蛋白13（PP13）含量與孕婦妊娠孕週長短的變化關繫。方法：迴顧性分析本院收治的44例子癇前期患者的臨床資料。將其分為輕度子癇前期組16例和重度子癇前期組28例；另外選擇30例正常健康孕婦設為對照組。採用ELISA檢測方法測定孕婦在不同孕週時血清中的PP13的含量。結果：輕、重度子癇前期組血清中PP13的含量均顯著高于正常孕婦組（P<0.05）；且重度子癇前期組顯著高于輕度子癇前期組（P<0.05）；各組妊娠晚期血清中PP13的含量顯著高于妊娠中期（P<0.05）；相對于妊娠中期，子癇前期組妊娠晚期孕婦血清中PP13含量的增加值顯著高于正常孕婦組（P<0.05）。結論：重度子癇前期孕婦血清中的PP13的含量高于輕度子癇前期孕婦，子癇前期患者血清中的PP13的含量高于正常孕婦，隨著妊娠時間的延長，孕婦血清內PP13的含量有所增高。
목적：연구탐토임신자간전기환자혈청중적태반단백13（PP13）함량여잉부임신잉주장단적변화관계。방법：회고성분석본원수치적44례자간전기환자적림상자료。장기분위경도자간전기조16례화중도자간전기조28례；령외선택30례정상건강잉부설위대조조。채용ELISA검측방법측정잉부재불동잉주시혈청중적PP13적함량。결과：경、중도자간전기조혈청중PP13적함량균현저고우정상잉부조（P<0.05）；차중도자간전기조현저고우경도자간전기조（P<0.05）；각조임신만기혈청중PP13적함량현저고우임신중기（P<0.05）；상대우임신중기，자간전기조임신만기잉부혈청중PP13함량적증가치현저고우정상잉부조（P<0.05）。결론：중도자간전기잉부혈청중적PP13적함량고우경도자간전기잉부，자간전기환자혈청중적PP13적함량고우정상잉부，수착임신시간적연장，잉부혈청내PP13적함량유소증고。
Objective:To study the serum placenta protein 13(PP13)content in patients with preeclampsia pregnancy and the changes of pregnant women pregnancy gestational length,to provide reference basis for diagnosis and treatment.Method:Clinical data of 44 patients with preeclampsia in our hospital were retrospectively analyzed. They were divided into the mild preeclampsia group(16 cases)and the severe preeclampsia group(28 cases );30 healthy women were selected as the control group. 74 cases of pregnant women in different gestational age were measured by the ELISA and placental protein 13 content in the serum of pregnant women were detected.Result:Content of PP13 in serum of patients with mild preeclampsia was significantly higher than normal pregnant women,there was statistically difference (P<0.05);Content of PP13 in serum of the severe preeclampsia group was significantly higher than the normal pregnant group,there was statistically difference(P<0.05);the placenta protein content 13 in serum of the severe preeclampsia group was significantly higher than that of the mild preeclampsia group,the result was statistically significant(P<0.05);the content placenta protein 13 of pregnant women in late pregnancy was significantly higher than that of pregnant women in early pregnancy,the result was statistically significant(P<0.05). The added value of 13 placenta protein content in serum of preeclampsia group was significantly higher than that of normal pregnant women(P<0.05).Conclusion:Placenta protein levels of pregnant women with severe preeclampsia is higher than that of pregnant women with mild preeclampsia, placenta protein 13 in patients with preeclampsia in the serum is higher than that in normal pregnant women,with length of pregnancy increasing,the content of placenta protein 13 in pregnant women with preeclampsia increases significantly.
