现代检验医学杂志
現代檢驗醫學雜誌
현대검험의학잡지
JOURNAL OF MODERN LABORATORY MEDICINE
2014年
2期
127-129
,共3页
流式细胞术%急性白血病%免疫分型
流式細胞術%急性白血病%免疫分型
류식세포술%급성백혈병%면역분형
flow cytometry%acute leukemia%imuunophenotyping
目的 分析急性白血病免疫分型的特点,为临床诊断提供快速准确的实验室依据.方法 回顾93例初发急性白血病的临床资料,采用流式细胞术进行骨髓免疫分型.结果 93例初发急性白血病中,急性髓系白血病(AML) 66例,其抗原表达从低到高依次为:CD7 (16.7%),CD15 (30.3%),CD71 (31.2%),CD11B (34.5%),CD34 (48.5%),CD117(50.0%),HLA-DR(65.2%),CD13(70%),CD33(86.4%)和CD38 (92.4%).急性B淋巴细胞白血病(B-ALL) 22例,其抗原表达从低到高依次为:CD34 (36.4%),CD20 (50.0%),CD38 (63.6%),CD10 (72.7%),HLA-DR (86.3%)和CD19(95.5%).急性T(T-ALL)淋巴细胞白血病5例,其抗原表达从低到高依次为:HLA-DR(60.0%),CD34 (60.0%),CD2(80.0%),CD7 (80.0%)和CD38(100.0%).结论 流式细胞术免疫分型能够快速、准确地为临床急性白血病的分型诊断提供依据.
目的 分析急性白血病免疫分型的特點,為臨床診斷提供快速準確的實驗室依據.方法 迴顧93例初髮急性白血病的臨床資料,採用流式細胞術進行骨髓免疫分型.結果 93例初髮急性白血病中,急性髓繫白血病(AML) 66例,其抗原錶達從低到高依次為:CD7 (16.7%),CD15 (30.3%),CD71 (31.2%),CD11B (34.5%),CD34 (48.5%),CD117(50.0%),HLA-DR(65.2%),CD13(70%),CD33(86.4%)和CD38 (92.4%).急性B淋巴細胞白血病(B-ALL) 22例,其抗原錶達從低到高依次為:CD34 (36.4%),CD20 (50.0%),CD38 (63.6%),CD10 (72.7%),HLA-DR (86.3%)和CD19(95.5%).急性T(T-ALL)淋巴細胞白血病5例,其抗原錶達從低到高依次為:HLA-DR(60.0%),CD34 (60.0%),CD2(80.0%),CD7 (80.0%)和CD38(100.0%).結論 流式細胞術免疫分型能夠快速、準確地為臨床急性白血病的分型診斷提供依據.
목적 분석급성백혈병면역분형적특점,위림상진단제공쾌속준학적실험실의거.방법 회고93례초발급성백혈병적림상자료,채용류식세포술진행골수면역분형.결과 93례초발급성백혈병중,급성수계백혈병(AML) 66례,기항원표체종저도고의차위:CD7 (16.7%),CD15 (30.3%),CD71 (31.2%),CD11B (34.5%),CD34 (48.5%),CD117(50.0%),HLA-DR(65.2%),CD13(70%),CD33(86.4%)화CD38 (92.4%).급성B림파세포백혈병(B-ALL) 22례,기항원표체종저도고의차위:CD34 (36.4%),CD20 (50.0%),CD38 (63.6%),CD10 (72.7%),HLA-DR (86.3%)화CD19(95.5%).급성T(T-ALL)림파세포백혈병5례,기항원표체종저도고의차위:HLA-DR(60.0%),CD34 (60.0%),CD2(80.0%),CD7 (80.0%)화CD38(100.0%).결론 류식세포술면역분형능구쾌속、준학지위림상급성백혈병적분형진단제공의거.