CAJ | 학술논문

Survivin(生存素)是凋亡抑制蛋白家族的新型成员，是目前发现的最强的凋亡抑制因子，与脑胶质瘤的发生和发展密切相关，参与细胞的分裂和增殖过程调节。鉴于和多数肿瘤相对关联性及组织分布的特点，为肿瘤临床诊断、治疗起到了很大的作用。 survivin可以作为肿瘤靶向治疗基因，它的发展有可能对基因水平是一个突破，因此survivin为肿瘤治疗的进一步研究铺平了道路。
Survivin(생존소)시조망억제단백가족적신형성원，시목전발현적최강적조망억제인자，여뇌효질류적발생화발전밀절상관，삼여세포적분렬화증식과정조절。감우화다수종류상대관련성급조직분포적특점，위종류림상진단、치료기도료흔대적작용。 survivin가이작위종류파향치료기인，타적발전유가능대기인수평시일개돌파，인차survivin위종류치료적진일보연구포평료도로。
Survivin is a new member of inhibitor of apoptosis protein family,is apoptosis inhibition factor mostly,related to the occurrence and development of glioma closely,division and proliferation processes involved in cell regulation. In view of the majority of tumors and relative relation and tissue distribution characteristics,a very significant role for tumor diagnosis,treatment. Survivin can be used as tumor targeting gene therapy,its development may is a breakthrough in gene level.