CAJ | 학술논문

目的：探讨宫颈液基薄层细胞学检查( Thinprep cytology test,TCT)与宫颈活检的符合率,结合宫颈活检在宫颈上皮性病变早期诊断中的临床应用价值。方法：回顾性分析2012年2122例妇科病人宫颈TCT 结果,阳性病例共106例,其中74例行宫颈活检,比较细胞学与组织学结果。结果：2122例 TCT 检查中细胞学检查阳性率为5.0%,其中ASC-US 73例(在阳性病例中占68.87%),ASC-H 5例(4.71%),LSIL 16例(15.09%),HSIL 11例(10.38%),SCC 1例(0.94%)；宫颈活检74例,其中炎性反应26例(35.14%),挖空细胞5例(6.76%), CINⅠ级48例(64.86%),CINⅡ级3例(4.05%),CIN Ⅲ级7例(9.46%),鳞癌2例(2.7%),以组织学结果验证细胞学结果,符合率分别为 LSIL(78.98%),HSIL(90.91%),SCC(100%)；并且宫颈病变多见于35~65岁年龄段。结论：宫颈 TCT 具有较高的准确性,是筛查宫颈上皮性病变的有效手段,结合阴道镜及宫颈活检进一步检查可使宫颈上皮内瘤变和宫颈癌得到早期诊断和早期治疗。
목적：탐토궁경액기박층세포학검사( Thinprep cytology test,TCT)여궁경활검적부합솔,결합궁경활검재궁경상피성병변조기진단중적림상응용개치。방법：회고성분석2012년2122례부과병인궁경TCT 결과,양성병례공106례,기중74례행궁경활검,비교세포학여조직학결과。결과：2122례 TCT 검사중세포학검사양성솔위5.0%,기중ASC-US 73례(재양성병례중점68.87%),ASC-H 5례(4.71%),LSIL 16례(15.09%),HSIL 11례(10.38%),SCC 1례(0.94%)；궁경활검74례,기중염성반응26례(35.14%),알공세포5례(6.76%), CINⅠ급48례(64.86%),CINⅡ급3례(4.05%),CIN Ⅲ급7례(9.46%),린암2례(2.7%),이조직학결과험증세포학결과,부합솔분별위 LSIL(78.98%),HSIL(90.91%),SCC(100%)；병차궁경병변다견우35~65세년령단。결론：궁경 TCT 구유교고적준학성,시사사궁경상피성병변적유효수단,결합음도경급궁경활검진일보검사가사궁경상피내류변화궁경암득도조기진단화조기치료。
Objective:To exploit the diagnose accordance rate of the cervical thinprep cytology test ( TCT ) and tissue biopsy, and to investigate the clinical application value of the TCT technology combined with tissue biopsy in early screening for cervical epithelial lesions. Methods:The results of 2122 cases with cervical TCT inspection were retrospective analyzed. Patients with ASC-US or severe than ASC - US were defined as abnormal cytology according to Bethesda system for cytology classifications. Among 106 cases of abnormal cytology,74 positive patiens received biopsy inspection. The cytology and histology results were compared, and the relationship of lesion and ages were analyzed. Results:In 2122 cases of cervical TCT,the abnormal cytology ratio was 5. 0%. Among them the ASC-US were 73 cases ( 68 . 9%) , ASC-H were 5 cases ( 4 . 71%) , LSIL were 16 cases (15. 09%),HSIL were 11 cases(10. 38%),and SCC were 2 cases(2. 7%). Among the 74 cases of biopsy,cases of inflammation reaction were 26 cases(35. 14%),koilocytotic cell 5 cases(6. 76%), CINⅠ48 cases(64. 86%),CINII3 cases(4. 05%),CIN Ⅲ 7 cases(9. 46%),squamous carcinoma 2 cases(2. 7%),revealing that the cytology results had a high conformity rate with biopsy results. And the onset age of cervical lesions was between 35-65 years old. Conclusion:TCT technology is an effective method for the screening of cervical epithelial lesions with its high accuracy. Combined with TCT and tissue biopsy can greatly improve early diagnosis of CIN and pretent the arising of c cervical carcinoma.