蚌埠医学院学报
蚌埠醫學院學報
방부의학원학보
ACTA ACADEMIAE MEDICINAE BENGBU
2014年
5期
609-611,615
,共4页
卵巢浆液性癌%早期诊断%临床分期%手术%化疗
卵巢漿液性癌%早期診斷%臨床分期%手術%化療
란소장액성암%조기진단%림상분기%수술%화료
ovarian serous carcinoma%early diagnosis%clinical stages%operation%chemotherapy%prognosis
目的：探讨影响卵巢浆液性癌生存预后的因素。方法：具有完整病历资料的卵巢浆液性癌患者54例,记录患者的年龄、临床表现、临床分期、辅助检查。患者均行手术治疗,其中41例早期患者行分期手术,13例晚期患者行肿瘤细胞减灭术。术后均行辅助化疗,其中化疗疗程≥6次38例,<6次16例,并对临床资料进行分析。结果：患者发病年龄高峰在50~59岁17例,最常见的症状是腹痛(43例)、阴道出血(7例)、腹胀(35例)、扪及腹块(15例)。术中冷冻存在漏诊,而单一辅助检查难以确诊,需联合应用。术后化疗≥6个疗程的患者生存率高于化疗<6个疗程的患者(P<0.05)。结论：卵巢癌筛查时应把肿瘤标志物的检测与症状、体征及影像学检查结合起来综合分析；提高术中冷冻的准确性尤为关键；肿瘤细胞减灭术,尽可能达到满意；术后尽量保证患者接受6次以上的化疗。
目的：探討影響卵巢漿液性癌生存預後的因素。方法：具有完整病歷資料的卵巢漿液性癌患者54例,記錄患者的年齡、臨床錶現、臨床分期、輔助檢查。患者均行手術治療,其中41例早期患者行分期手術,13例晚期患者行腫瘤細胞減滅術。術後均行輔助化療,其中化療療程≥6次38例,<6次16例,併對臨床資料進行分析。結果：患者髮病年齡高峰在50~59歲17例,最常見的癥狀是腹痛(43例)、陰道齣血(7例)、腹脹(35例)、捫及腹塊(15例)。術中冷凍存在漏診,而單一輔助檢查難以確診,需聯閤應用。術後化療≥6箇療程的患者生存率高于化療<6箇療程的患者(P<0.05)。結論：卵巢癌篩查時應把腫瘤標誌物的檢測與癥狀、體徵及影像學檢查結閤起來綜閤分析；提高術中冷凍的準確性尤為關鍵；腫瘤細胞減滅術,儘可能達到滿意；術後儘量保證患者接受6次以上的化療。
목적：탐토영향란소장액성암생존예후적인소。방법：구유완정병력자료적란소장액성암환자54례,기록환자적년령、림상표현、림상분기、보조검사。환자균행수술치료,기중41례조기환자행분기수술,13례만기환자행종류세포감멸술。술후균행보조화료,기중화료료정≥6차38례,<6차16례,병대림상자료진행분석。결과：환자발병년령고봉재50~59세17례,최상견적증상시복통(43례)、음도출혈(7례)、복창(35례)、문급복괴(15례)。술중냉동존재루진,이단일보조검사난이학진,수연합응용。술후화료≥6개료정적환자생존솔고우화료<6개료정적환자(P<0.05)。결론：란소암사사시응파종류표지물적검측여증상、체정급영상학검사결합기래종합분석；제고술중냉동적준학성우위관건；종류세포감멸술,진가능체도만의；술후진량보증환자접수6차이상적화료。
Objective:To investigate the factors affecting the survival prognosis of patients with ovarian serous carcinoma. Methods:Fifty-four patients with ovarian serous carcinoma were included in the study. The age,clinical manifestation,clinical stage and additional tests of the patients were analyzed. All the patients underwent surgical treatment. Forty-one early-stage cases were performed staging surgeries and 13 advanced cases cytoreductive surgeries. All of them received postoperative adjuvant chemotherapy. Thirty-eight cases received not less than 6 courses of chemotherapy and 16 cases less than 6 courses. Results:The peak age of onset was between 50 and 59,and the most common symptoms were abdominal pain(43 cases),vaginal bleeding(7 cases),abdominal distension(35 cases) and palpable abdominal mass(15 cases). Miss-diagnosis often occurred in intraoperative frozen and it was difficult to make a diagnosis by a single auxiliary examination,so combined examination was necessary. The survival rate of the patients having received not less than 6 courses of postoperative chemotherapy was high than that of patients having received less than 6 courses(P<0. 05). Conclusions:The screening of ovarian cancer should use a comprehensive analysis combining the detection of tumor markers, symptoms, physical signs and imaging;It is particularly important to improve the accuracy of intraoperative frozen;Effective cytoreductive surgery is essential;The patients should be assured to receive not less than 6 courses of postoperative chemotherapy.
