中华老年心脑血管病杂志
中華老年心腦血管病雜誌
중화노년심뇌혈관병잡지
CHINESE JOURNAL OF GERIATRIC CARDIOVASCULAR AND CEREBROVASCULAR DISEASES
2014年
6期
571-573
,共3页
陈涛%张春晓%米杰%钟明惠%田刚%周定%孙中华%齐向前
陳濤%張春曉%米傑%鐘明惠%田剛%週定%孫中華%齊嚮前
진도%장춘효%미걸%종명혜%전강%주정%손중화%제향전
冠心病%药物洗脱支架%冠状动脉再狭窄%纤维蛋白原%胆红素
冠心病%藥物洗脫支架%冠狀動脈再狹窄%纖維蛋白原%膽紅素
관심병%약물세탈지가%관상동맥재협착%섬유단백원%담홍소
coronary disease%drug-eluting stents%coronary restenosis%fibrinogen%bilirubin
目的:探讨冠状动脉药物洗脱支架术后支架内再狭窄与血清总胆红素(T B )和纤维蛋白原(Fib )的关系。方法收集PCI置入药物洗脱支架术后1年行冠状动脉造影随访的782例患者,分为再狭窄组130例和对照组652例。回顾性分析2组患者临床资料的差异。结果再狭窄组与无再狭窄组患者血清TB[(11.82±4.53)μmol/L vs (12.95±5.06)μmol/L]、Fib[(3.04±0.65)g/L vs (2.83±0.60)g/L]比较,差异有统计学意义(P<0.05,P<0.01)。支架内再狭窄与糖尿病(OR=1.763,95% CI:1.158~2.683)、Fib(OR=1.678,95% CI:1.242~2.266)呈正相关,与血清TB(OR=0.922,95% CI:0.860~0.988)、支架直径(OR=0.615,95% CI:0.444~0.850)呈负相关。结论糖尿病、Fib为支架内再狭窄的危险因素,支架直径和血清T B为支架内再狭窄保护因素。
目的:探討冠狀動脈藥物洗脫支架術後支架內再狹窄與血清總膽紅素(T B )和纖維蛋白原(Fib )的關繫。方法收集PCI置入藥物洗脫支架術後1年行冠狀動脈造影隨訪的782例患者,分為再狹窄組130例和對照組652例。迴顧性分析2組患者臨床資料的差異。結果再狹窄組與無再狹窄組患者血清TB[(11.82±4.53)μmol/L vs (12.95±5.06)μmol/L]、Fib[(3.04±0.65)g/L vs (2.83±0.60)g/L]比較,差異有統計學意義(P<0.05,P<0.01)。支架內再狹窄與糖尿病(OR=1.763,95% CI:1.158~2.683)、Fib(OR=1.678,95% CI:1.242~2.266)呈正相關,與血清TB(OR=0.922,95% CI:0.860~0.988)、支架直徑(OR=0.615,95% CI:0.444~0.850)呈負相關。結論糖尿病、Fib為支架內再狹窄的危險因素,支架直徑和血清T B為支架內再狹窄保護因素。
목적:탐토관상동맥약물세탈지가술후지가내재협착여혈청총담홍소(T B )화섬유단백원(Fib )적관계。방법수집PCI치입약물세탈지가술후1년행관상동맥조영수방적782례환자,분위재협착조130례화대조조652례。회고성분석2조환자림상자료적차이。결과재협착조여무재협착조환자혈청TB[(11.82±4.53)μmol/L vs (12.95±5.06)μmol/L]、Fib[(3.04±0.65)g/L vs (2.83±0.60)g/L]비교,차이유통계학의의(P<0.05,P<0.01)。지가내재협착여당뇨병(OR=1.763,95% CI:1.158~2.683)、Fib(OR=1.678,95% CI:1.242~2.266)정정상관,여혈청TB(OR=0.922,95% CI:0.860~0.988)、지가직경(OR=0.615,95% CI:0.444~0.850)정부상관。결론당뇨병、Fib위지가내재협착적위험인소,지가직경화혈청T B위지가내재협착보호인소。
Objective To study the relation of stent restenosis (SR) with serum bilirubin and fi-brinogen level in CHD patients after drug eluting .Methods Seven hundred and eighty-two CHD patients who were followed up 1 year after PCI and drug eluting stent implantation in our hospital were divided into SR group (n=130) and control group (n=652) .Clinical data ,biochemical and coronary angiohraphy parameters about the two groups were retrospectively analyzed .Their rela-tion with SR was analyzed by multivariate logistic regression analysis .Results The incidence of diabete mellitus (DM ) and hyperlipoidemia ,the serum level of total bilirubin and fibrinogen and the stent diameter were significantly different in the two groups (P< 0 .05 ,P< 0 .01) .The SR was positively related with DM and serum fibrinogen level (OR=1 .763 ,95% CI:1 .158 -2 .683 ;OR=1 .678 ,95% CI:1 .242-2.266) .However ,the SR was negatively related with the serum level of total bilirubin and stent diameter (OR=0 .922 ,95% CI:0 .860 -0 .988 ;OR= 0 .615 ,95% CI:0.444-0.850 ) .Conclusion DM and serum fibrinogen level are the risk factors for SR w hile stent diameter and serum level of total bilirubin are the protective factors for SR .