CAJ | 학술논문

目的：评价海参冻干粉治疗更年期综合征肾阳虚证的临床疗效，并观察其对患者性激素水平的影响。方法将60例更年期综合征肾阳虚证患者按照随机数字表法分为对照组和治疗组两组，每组30例。观察两组患者治疗前后患者临床疗效及血清雌二醇、促卵泡激素、促黄体生成激素水平的变化。结果治疗组和对照组的患者血清促卵泡激素、促黄体生成激素水平均明显降低，雌二醇水平均升高，与治疗前比较有显著性差异(P<0．05)，治疗组与对照组比较，血清雌二醇、促卵泡激素及促黄体生成激素没有显著差异(P>0．05)；临床疗效比较，治疗组总有效率为90%；对照组总有效率为93．33%，治疗组与对照组没有显著差异( P>0．05)。结论海参冻干粉对更年期综合征肾阳虚证患者具有较好的治疗作用，对性激素水平有调节作用。
목적：평개해삼동간분치료경년기종합정신양허증적림상료효，병관찰기대환자성격소수평적영향。방법장60례경년기종합정신양허증환자안조수궤수자표법분위대조조화치료조량조，매조30례。관찰량조환자치료전후환자림상료효급혈청자이순、촉란포격소、촉황체생성격소수평적변화。결과치료조화대조조적환자혈청촉란포격소、촉황체생성격소수평균명현강저，자이순수평균승고，여치료전비교유현저성차이(P<0．05)，치료조여대조조비교，혈청자이순、촉란포격소급촉황체생성격소몰유현저차이(P>0．05)；림상료효비교，치료조총유효솔위90%；대조조총유효솔위93．33%，치료조여대조조몰유현저차이( P>0．05)。결론해삼동간분대경년기종합정신양허증환자구유교호적치료작용，대성격소수평유조절작용。
Objective To evaluate the efficacy of freeze-dried sea cucumber powder on the treat-ment of kidney-yang deficiency of perimenopause syndrome, and study its effect on the levels of gonadal hormone. Methods 60 cases of kidney-yang deficiency of perimenopause syndrome in order to diagnosis were randomly divided into a control group and a treatment group, 30 cases in each group. Observe the changes in the clinical effectiveness and the levels of serum E2 , FSH and LH before and after treatment. Results After treatment, the level of serum E2 of both groups were inereased significantly(P>0. 05);the levels of serum FSH and LH were increased significantly ( P>0. 05 ) . Comparison between the treatment group and the control group, no significant differences in the levels of serum E2 , FSH and LH ( P >0. 05). Comparison of the clinical effectiveness, the total effective rate of treatment group was 90%. The control group the total effective rate was 93. 33%, no significant differences among treatment groups and con-trol group ( P>0. 05 ) . Conclusion Freeze-dried sea cucumber powder in the patients with kidney-yang deficiency of perimenopause syndrome has preferable clinical effects and can modify gonadal hormone level.