CAJ | 학술논문

药物代谢组学是通过用药前代谢产物的特点来预测对个人进行药物或外来物干预的结果，主要目标是寻找出与疾病相关的、具有个体差异、能代表个体代谢水平的生物标记物或生物标记组，对药物安全性评价及个体化治疗将起到重要作用。
약물대사조학시통과용약전대사산물적특점래예측대개인진행약물혹외래물간예적결과，주요목표시심조출여질병상관적、구유개체차이、능대표개체대사수평적생물표기물혹생물표기조，대약물안전성평개급개체화치료장기도중요작용。
Pharmaco-metabonomics can predict the outcome of a drug or xenobiotic intervention in an individual based on a mathematical model of pre-intervention metabolite signatures.Its main objective is to find disease-related biomarkers or biomarkers group with individual differ-ences and on behalf of individual metabolism.Pharmaco-metabonomics will play an important role in drug safety evaluation and individualized therapy.