国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
11期
1445-1446
,共2页
梁卓夫%邝璐%谢永强%刘旻%廖春淼
樑卓伕%鄺璐%謝永彊%劉旻%廖春淼
량탁부%광로%사영강%류민%료춘묘
医院内感染%病原菌%耐药性%儿童
醫院內感染%病原菌%耐藥性%兒童
의원내감염%병원균%내약성%인동
infection%pathogenic bacteria%drugs resistance%child
目的：了解和分析儿童医院内呼吸道感染的病原菌分布及其耐药状况，为防控医院内感染提供科学依据。方法对396例医院内感染儿童患者送检的上呼吸道标本按常规方法进行微生物培养，并用 K-B 法测定细菌对临床常用抗菌药物的敏感性。结果396例上呼吸道标本中，有225例共分离出微生物234株，阳性分离率为56．8％（225/396）；分离出的234株病原菌中，革兰阴性菌的构成比为72．6％（170/234），其中以克雷伯菌属的检出率最高，为49．4％（84/170）。革兰阳性菌的构成比为23．5％（55/234），以葡萄球菌属的检出率较高，为58．2％（32/55）。234株病原菌对9种临床常用的抗菌药物敏感率较高的是亚胺培南，其次是氨基糖苷类。结论对儿童患者有感染症侯的有必要留取上呼吸道标本做细菌学检查和药物敏感性试验。
目的：瞭解和分析兒童醫院內呼吸道感染的病原菌分佈及其耐藥狀況，為防控醫院內感染提供科學依據。方法對396例醫院內感染兒童患者送檢的上呼吸道標本按常規方法進行微生物培養，併用 K-B 法測定細菌對臨床常用抗菌藥物的敏感性。結果396例上呼吸道標本中，有225例共分離齣微生物234株，暘性分離率為56．8％（225/396）；分離齣的234株病原菌中，革蘭陰性菌的構成比為72．6％（170/234），其中以剋雷伯菌屬的檢齣率最高，為49．4％（84/170）。革蘭暘性菌的構成比為23．5％（55/234），以葡萄毬菌屬的檢齣率較高，為58．2％（32/55）。234株病原菌對9種臨床常用的抗菌藥物敏感率較高的是亞胺培南，其次是氨基糖苷類。結論對兒童患者有感染癥侯的有必要留取上呼吸道標本做細菌學檢查和藥物敏感性試驗。
목적：료해화분석인동의원내호흡도감염적병원균분포급기내약상황，위방공의원내감염제공과학의거。방법대396례의원내감염인동환자송검적상호흡도표본안상규방법진행미생물배양，병용 K-B 법측정세균대림상상용항균약물적민감성。결과396례상호흡도표본중，유225례공분리출미생물234주，양성분리솔위56．8％（225/396）；분리출적234주병원균중，혁란음성균적구성비위72．6％（170/234），기중이극뢰백균속적검출솔최고，위49．4％（84/170）。혁란양성균적구성비위23．5％（55/234），이포도구균속적검출솔교고，위58．2％（32/55）。234주병원균대9충림상상용적항균약물민감솔교고적시아알배남，기차시안기당감류。결론대인동환자유감염증후적유필요류취상호흡도표본주세균학검사화약물민감성시험。
Objective To understand and analysis of the pathogens distribution and drug resistance of nosocomial infection in children′s hospital,so as to provide reliable scientific basis for the prevention and control of hospital infection.Methods 396 cases of upper respiratory tract specimens were collected from pediatric patients with nosocomial infection.These specimens were detected by sputum specimens conventional methods of microorganism cultivation,and K-B method was used to determine the bacteria sensi-tivities to clinical common drug.Results There were 225 cases of specimens were pathogen positive among all the 396 specimens, and 234 strains of bacteria were isolated in all.The positive isolated rate was 56.8%(225/396).Among the 234 isolated strains, Gram negative bacteria accounted for 72.6%(170/234),and Klebsiella occupied the first place[49.4%(84/170)].Gram positive bacteria accounted for 23.5%(55/234),and Staphylococcus had the highest isolated rate in Gram positive bacteria[58.2% (32/55)].In all the 9 kinds of clinical common antimicrobial agents,imipenem had high drug sensitivity to the 234 isolated strains,and the aminoglycosides came next.Conclusion It is necessary for the pediatric patients with nosocomial infection to collect upper re-spiratory tract specimens for bacteriologic studies and drug sensitivity tests.
