CAJ | 학술논문

目的：研究半乳糖凝集素3对急性缺血性脑卒中患者预后评估的价值。方法选取165例急性缺血性脑卒中患者，追踪随访观察12个月，记录复发脑卒中事件的情况，并检测其血清半乳糖凝集素3的浓度。结果至随访截止，165例急性缺血性脑卒中患者中共有65例患者在12个月内再次发生脑卒中事件，复发率为39．39％。复发脑卒中患者的血清半乳糖凝集素3水平显著高于无复发的患者，差异有统计学意义（P ＜0．05）。半乳糖凝集素3高水平患者复发脑卒中的比例显著高于低水平患者，差异有统计学意义（P ＜0．05）。结论半乳糖凝集素3是预测急性缺血性脑卒中患者预后的良好指标，该指标的检测有助于对患者进行复发危险评估。
목적：연구반유당응집소3대급성결혈성뇌졸중환자예후평고적개치。방법선취165례급성결혈성뇌졸중환자，추종수방관찰12개월，기록복발뇌졸중사건적정황，병검측기혈청반유당응집소3적농도。결과지수방절지，165례급성결혈성뇌졸중환자중공유65례환자재12개월내재차발생뇌졸중사건，복발솔위39．39％。복발뇌졸중환자적혈청반유당응집소3수평현저고우무복발적환자，차이유통계학의의（P ＜0．05）。반유당응집소3고수평환자복발뇌졸중적비례현저고우저수평환자，차이유통계학의의（P ＜0．05）。결론반유당응집소3시예측급성결혈성뇌졸중환자예후적량호지표，해지표적검측유조우대환자진행복발위험평고。
Objective To evaluate the prognosis value of the expression of galectin 3 in patients with acute ischemic stroke. Methods 165 Patients with acute ischemic stroke had been observated for 12 months and their occurrence of recurrent stroke e-vents were recorded.The concentration of galectin-3 was detected.Results 65 patients had recurrence stroke events with a rate of 39.39% within 12 months.It was also found that the serum concentration of galectin-3 in acute ischemic stroke recurrence patients were significantly higher than those of patients without recurrence,the difference was statistically significant(P <0.05).The rate of acute ischemic stroke recurrence in patients with high concentrations of galectin-3 was higher than that in patients with low concen-trations of galectin-3,the difference was statistically significant(P <0.05).Conclusion Galectin-3 is a good indicator to predict the prognosis of patients with acute ischemic stroke,and it could be used to evaluate the risk of recurrence in patients.