国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
11期
1397-1399
,共3页
唐三梅%吴兴中%黄进梅%郑和平%薛耀华%曾维英%覃晓琳%欧江丽%李奕歆%蓝银苑%方铭恒%许巧珍%白顺
唐三梅%吳興中%黃進梅%鄭和平%薛耀華%曾維英%覃曉琳%歐江麗%李奕歆%藍銀苑%方銘恆%許巧珍%白順
당삼매%오흥중%황진매%정화평%설요화%증유영%담효림%구강려%리혁흠%람은원%방명항%허교진%백순
支原体%泌尿道%耐药
支原體%泌尿道%耐藥
지원체%비뇨도%내약
Mycoplasma%urinary tract%drug resistance
目的:分析性病门诊泌尿生殖道解脲脲原体(Uu)和人型支原体(Mh)的感染及药敏情况,为临床提供最新用药依据。方法采用支原体培养、鉴定、药敏试剂盒,对2008~2012年性病门诊4229例疑诊患者进行 Uu 和 Mh 检测及药敏试验。结果4229例标本中检出支原体1171例,总阳性率27.69%,其中单纯 Uu 感染1058例(90.36%),单纯 Mh 感染38例(3.24%),Uu 和 Mh 混合感染75例(6.40%)。单纯 Uu 感染对交沙霉素、克拉霉素、罗红霉素的耐药率较低,依次为1.04%、5.10%、5.19%;单纯 Mh 感染对交沙霉素、多西环素、四环素的耐药率较低,依次为0、2.63%、7.89%;Uu 和 Mh 混合感染对环丙沙星和红霉素耐药率最高,分别为84.00%和73.33%。2008年支原体感染率最低(25.50%),2011年最高(29.10%)。10种药物的5年耐药率差异不具有统计学意义(P >0.05)。结论Uu 是支原体感染的主要病原体;交沙霉素、多西环素可以作为该地区支原体混合感染的首选药物;近5年支原体感染有上升趋势,但支原体耐药性得到一定的控制,应在此基础上加强对耐药菌株的控制,增加药敏检测,为进行耐药监测、临床合理使用抗菌药物,提高疗效据。
目的:分析性病門診泌尿生殖道解脲脲原體(Uu)和人型支原體(Mh)的感染及藥敏情況,為臨床提供最新用藥依據。方法採用支原體培養、鑒定、藥敏試劑盒,對2008~2012年性病門診4229例疑診患者進行 Uu 和 Mh 檢測及藥敏試驗。結果4229例標本中檢齣支原體1171例,總暘性率27.69%,其中單純 Uu 感染1058例(90.36%),單純 Mh 感染38例(3.24%),Uu 和 Mh 混閤感染75例(6.40%)。單純 Uu 感染對交沙黴素、剋拉黴素、囉紅黴素的耐藥率較低,依次為1.04%、5.10%、5.19%;單純 Mh 感染對交沙黴素、多西環素、四環素的耐藥率較低,依次為0、2.63%、7.89%;Uu 和 Mh 混閤感染對環丙沙星和紅黴素耐藥率最高,分彆為84.00%和73.33%。2008年支原體感染率最低(25.50%),2011年最高(29.10%)。10種藥物的5年耐藥率差異不具有統計學意義(P >0.05)。結論Uu 是支原體感染的主要病原體;交沙黴素、多西環素可以作為該地區支原體混閤感染的首選藥物;近5年支原體感染有上升趨勢,但支原體耐藥性得到一定的控製,應在此基礎上加彊對耐藥菌株的控製,增加藥敏檢測,為進行耐藥鑑測、臨床閤理使用抗菌藥物,提高療效據。
목적:분석성병문진비뇨생식도해뇨뇨원체(Uu)화인형지원체(Mh)적감염급약민정황,위림상제공최신용약의거。방법채용지원체배양、감정、약민시제합,대2008~2012년성병문진4229례의진환자진행 Uu 화 Mh 검측급약민시험。결과4229례표본중검출지원체1171례,총양성솔27.69%,기중단순 Uu 감염1058례(90.36%),단순 Mh 감염38례(3.24%),Uu 화 Mh 혼합감염75례(6.40%)。단순 Uu 감염대교사매소、극랍매소、라홍매소적내약솔교저,의차위1.04%、5.10%、5.19%;단순 Mh 감염대교사매소、다서배소、사배소적내약솔교저,의차위0、2.63%、7.89%;Uu 화 Mh 혼합감염대배병사성화홍매소내약솔최고,분별위84.00%화73.33%。2008년지원체감염솔최저(25.50%),2011년최고(29.10%)。10충약물적5년내약솔차이불구유통계학의의(P >0.05)。결론Uu 시지원체감염적주요병원체;교사매소、다서배소가이작위해지구지원체혼합감염적수선약물;근5년지원체감염유상승추세,단지원체내약성득도일정적공제,응재차기출상가강대내약균주적공제,증가약민검측,위진행내약감측、림상합리사용항균약물,제고료효거。
Objective To analyze Ureaplasma urealyticum (Uu)or Mycoplasma hominis (Mh)infections of urogenital tract and resistance trends in sexually transmitted disease(STD)outpatient,so as to provide new reference for drug administration in clinic. Methods 4 229 cases of clinical doubtful patients of STD outpatient were enrolled from 2008 to 2012.Uu and Mh were detected and drug sensitivity test were performed by Mycoplasma IST kit.Results In 4 229 cases,1 171 were Mycoplasma positive (27.69%),including 1 058 cases of Uu infection(90.36%),38 cases of Mh(3.24%)infection,and 75 cases of mixed(Uu+Mh)in-fection(6.40%).Uu showed low resistance rates to josamycine,clarithromycin,and roxithromycin,which were 1.04%,5.10%, and 5.19%,respectively.Mh showed low resistance rates to josamycine(0),deoxytetracycline(2.63%),and tetracycline(7.89%). Mixed infections showed high resistance rates to ciprofloxacin(84.00%)and erythromycin(73.33%).The Mycoplasma infection rate was the lowest in 2008(25.50%),and the highest in 2011(29.10%).There was no significant difference among the drug re-sistant rates of all the 10 kinds of drugs in the past five years(P >0.05).Conclusion The main pathogens of Mycoplasma infec-tion is Uu.Josamycine and deoxytetracycline can be used as the first choice in Mycoplasma treatment.In the past five years,Myco-plasma infection rates show an upward trend,but the drug resistance rates have been controled.Clinic treatment should be based on the drug susceptibility test so as to prevent the drug-resistant stains from increasing and spreading,and provide the basis for drug resistance surveillance and rational use of medicines to improve the curative effect.