CAJ | 학술논문

剖宫产是解决难产和许多产科难题，挽救产妇和围产儿的有效手段。术后感染是最常见并发症，并发感染的代价很高，围术期预防性抗菌药物的正确使用有助于降低术后感染率，减少产儿死亡。针对剖宫产预防用抗菌药物的选择、给药时机（切皮前或结扎脐带后）、给药时程，对新生儿的影响以及我国预防用抗菌药物使用现状，综述国内外用药指南及大量研究数据，以期为临床医师提供示范性指导及丰富的理论参考数据，促进临床合理用药。
부궁산시해결난산화허다산과난제，만구산부화위산인적유효수단。술후감염시최상견병발증，병발감염적대개흔고，위술기예방성항균약물적정학사용유조우강저술후감염솔，감소산인사망。침대부궁산예방용항균약물적선택、급약시궤（절피전혹결찰제대후）、급약시정，대신생인적영향이급아국예방용항균약물사용현상，종술국내외용약지남급대량연구수거，이기위림상의사제공시범성지도급봉부적이론삼고수거，촉진림상합리용약。
Cesarean section, which is an predominant method to resolve obstetric problems, playing an important role in saving lives of maternal and perinatal. Postoperative infection is the most common complication with high price. Reasonable application of antibacterials during perioperative period can decrease the rates of postoperative infection and perinatal death. Base on international guidelines and previous research data, this review focus on major subjects about the status of antibacterials application in China, such as how to choose appropriate preventative antibacterial, determine the exact program and timing of administration (before skin incision or after the umbilical cord ligation), and anticipate the subsequent adverse effects on newborns during perioperative period. Understanding the efficacy and complication of antibacterials prophylaxis for cesarean section during perioperative period will provide substantial administrate reference for the therapeutic application and establish the guidelines for clinical observation.