CAJ | 학술논문

目的：探讨两种剂量替罗非班治疗老年不稳定型心绞痛疗效差异。方法：选择80例不稳定型心绞痛老年患者，随机分为观察组和对照组。对照组给予常规剂量替罗非班治疗，观察组给予小剂量替罗非班治疗。评定两组治疗效果。观察心电图改变情况。结果：观察组治疗后ST段下移幅度和对照组治疗后比较，差异无统计学意义（ P>0.05）。观察组总有效率与对照组比较，差异无统计学意义（P>0.05）。观察组不良反应发生率低于对照组不良反应发生率，差异有统计学意义（P<0.05）。结论：小剂量替罗非班治疗老年不稳定型心绞痛效果显著，有助于减少用药不良反应，值得借鉴。
목적：탐토량충제량체라비반치료노년불은정형심교통료효차이。방법：선택80례불은정형심교통노년환자，수궤분위관찰조화대조조。대조조급여상규제량체라비반치료，관찰조급여소제량체라비반치료。평정량조치료효과。관찰심전도개변정황。결과：관찰조치료후ST단하이폭도화대조조치료후비교，차이무통계학의의（ P>0.05）。관찰조총유효솔여대조조비교，차이무통계학의의（P>0.05）。관찰조불량반응발생솔저우대조조불량반응발생솔，차이유통계학의의（P<0.05）。결론：소제량체라비반치료노년불은정형심교통효과현저，유조우감소용약불량반응，치득차감。
Objective To explore the effect of two different doses of tirofibanin on elderly patients with unstable angina pecto-ris. Method 80 elderly patients with unstable angina were selected and randomly divided into observation group and control group. The control group was given conventional dose of tirofibanin,the observation group was given low dose tirofiban. Evaluation of the therapeutic effects was done in two groups. The electrocardiogram was observed. Results The ST segment depression scale in the observation group after treatment compared with that in the control group after treatment,there was no difference statistics significance(P>0. 05). the clinical total effective rate in the observation group compared that in the control group,there was no difference statistics significance(P>0. 05). the inci-dence of adverse reactions in the observation group was lower than in the control group,the difference was statistically significant( P<0. 05). Conclusion Low dose of tirofiban on elderly patients with unstable angina pectoris has significant effect,and may reduce adverse reaction,the therapy is worth learning from.