CAJ | 학술논문

目的：探讨胰激肽原酶对面神经炎的治疗效果。方法：选择诊断明确面神经炎患者85例，随机分为观察组44例和对照组41例，两组均给予常规的面神经炎治疗，观察组加用胰激肽原酶20 U，1次/d肌内注射，连续14 d。治疗2周、4周、6周后，采用Sunnybrook分级法（SBGS）测量患者的面肌麻痹评分情况。结果：观察组治疗2周后，面神经麻痹评分由（16.6±3.6）分上升至（50.2±3.8）分，4周后，上升至（75.9±2.4）分，6周后，上升至（90.9±2.5）分，总有效率93.2%，均明显优于对照组（ P<0.05）。结论：面神经炎患者加用胰激肽原酶治疗后，面神经麻痹症状显著改善，不良反应发生少。
목적：탐토이격태원매대면신경염적치료효과。방법：선택진단명학면신경염환자85례，수궤분위관찰조44례화대조조41례，량조균급여상규적면신경염치료，관찰조가용이격태원매20 U，1차/d기내주사，련속14 d。치료2주、4주、6주후，채용Sunnybrook분급법（SBGS）측량환자적면기마비평분정황。결과：관찰조치료2주후，면신경마비평분유（16.6±3.6）분상승지（50.2±3.8）분，4주후，상승지（75.9±2.4）분，6주후，상승지（90.9±2.5）분，총유효솔93.2%，균명현우우대조조（ P<0.05）。결론：면신경염환자가용이격태원매치료후，면신경마비증상현저개선，불량반응발생소。
Objective Clinical experiments were conducted to observe the effects of pancreatic kininogenase in treating facial neuri-tis. Method 85 cases of facial neuritis were randomly divided into control group(41cases)and treatment group(44 cases). Basing on conventional therapy to both groups,an additional 20 units pancreatic kininogenase by intramuscular injection 1/d for two weeks was applied to the treatment group. The Sunnybrook Facial Grading System( SBGS)was used to assess facial movement outcomes of the patients after 2 weeks,4 weeks and 6 weeks respectively. Results Result showed that the Sunnybrook scores of treatment group increased from(16. 6 ± 3. 6)to(50. 2 ± 3. 8)after 2 weeks' treating,to(75. 9 ± 2. 4)after 4 weeks' treating and(90. 9 ± 2. 5)after 6 weeks' treating,which were respectively higher than those of the control group( P<0. 001);the total effective rate of the treatment group was 93. 2% for 6 weeks' treating,which were respectively higher than those of the control group( P<0. 005). Conclusion Treatment with pancreatic kininogenase is effective in reducing facial synkinesis with little adverse reactions in patients with Bell's palsy.