CAJ | 학술논문

目的：观察蓝光联合复方氯霉素洗剂治疗寻常型痤疮的临床疗效。方法：将116例寻常型痤疮患者随机分为治疗组、对照1组和对照2组，治疗组40例照射蓝光，每周2次；外用复方氯霉素洗剂2次/d，8周为一个疗程；对照1组36例照射蓝光，每周2次，8周为一个疗程；对照2组40例外用复方氯霉素洗剂2次/d，8周为一个疗程。结果：治疗组有效率为92.5%；对照1组有效率为72.22%；对照2组有效率为62.5%；治疗组患者有效明显高于对照1组及对照2组（χ2=4.158，P=0.041；χ2=8.674，P=0.003），对照1组及对照2组患者有效率差异无统计学意义（χ2=0.811，P=0.368）。三组患者均无明显不良反应。结论：蓝光联合复方氯霉素洗剂治疗寻常型痤疮是有效、安全的。
목적：관찰람광연합복방록매소세제치료심상형좌창적림상료효。방법：장116례심상형좌창환자수궤분위치료조、대조1조화대조2조，치료조40례조사람광，매주2차；외용복방록매소세제2차/d，8주위일개료정；대조1조36례조사람광，매주2차，8주위일개료정；대조2조40예외용복방록매소세제2차/d，8주위일개료정。결과：치료조유효솔위92.5%；대조1조유효솔위72.22%；대조2조유효솔위62.5%；치료조환자유효명현고우대조1조급대조2조（χ2=4.158，P=0.041；χ2=8.674，P=0.003），대조1조급대조2조환자유효솔차이무통계학의의（χ2=0.811，P=0.368）。삼조환자균무명현불량반응。결론：람광연합복방록매소세제치료심상형좌창시유효、안전적。
Objective To observe the clinical effect and safety of blue light phototherapy combined with compound indomethacin tinc-ture in treatment of acne vulgaris. Method One hundred and twenty-five cases with acne vulgaris were divided into treatment group,con-trol group 1 and control group 2 at randomly. Forty patients in the treatment group treated with blue light phototherapy 2 times every week, externally used compound indomethacin tincture twice daily for 8 weeks. Thirty-six patients in the control group 1 treated with blue light phototherapy 2 times every week for 8 weeks. Forty patients in the control group 2 treated with compound indomethacin tincture twice daily for 8 weeks. Results The clinical effective rate was 92. 5%,72. 22% and 62. 5% in the treatment group,control group 1 and control group 2,respectively. The clinical effective rate of treatment group was significant higher than that of control group 1 and control group 2(χ2 =4. 158,P=0. 041;χ2 =8. 674,P= 0. 003). The clinical effective rate of control group 1 was no significant with control group 2(χ2 =0. 811,P= 0. 368). No marked side effects were observed in three groups. Conclusion The blue light phototherapy combined with com-pound indomethacin tincture is efficacy and safety in the treatment of acne vulgaris.