河北医学
河北醫學
하북의학
HEBEI MEDICINE
2014年
1期
48-51
,共4页
2型糖尿病%肺结核病%耐药性%危险因素
2型糖尿病%肺結覈病%耐藥性%危險因素
2형당뇨병%폐결핵병%내약성%위험인소
Type 2 diabetes mellitus%Pulmonary tuberculosis%Drug resistant%Risk factor
目的：分析2型糖尿病（T2DM）合并肺结核患者产生耐药性的相关危险因素。方法：选取248例我院治疗的结核病患者，依据是否合并T2DM分为：研究组，98例，合并T2DM；对照组，150例，未合并T2 DM。收集两组的临床资料，通过回归分析产生耐药性的相关危险因素。结果：经应用单因素卡方检验，农村居民、居住条件差、治疗不持续、病程时间较长、依从性差、吸烟、HbA1 c 值、BMI值、高脂血症等为相关危险因素，再经多因素非条件Logistic 回归分析显示，治疗不持续、病程超过1年、依从性差、吸烟、HbA1 c值为发生耐药的相关危险因素。结论：治疗过程有中断、病程长、依从性差以及血糖控制不佳的患者易出现耐药性。
目的：分析2型糖尿病（T2DM）閤併肺結覈患者產生耐藥性的相關危險因素。方法：選取248例我院治療的結覈病患者，依據是否閤併T2DM分為：研究組，98例，閤併T2DM；對照組，150例，未閤併T2 DM。收集兩組的臨床資料，通過迴歸分析產生耐藥性的相關危險因素。結果：經應用單因素卡方檢驗，農村居民、居住條件差、治療不持續、病程時間較長、依從性差、吸煙、HbA1 c 值、BMI值、高脂血癥等為相關危險因素，再經多因素非條件Logistic 迴歸分析顯示，治療不持續、病程超過1年、依從性差、吸煙、HbA1 c值為髮生耐藥的相關危險因素。結論：治療過程有中斷、病程長、依從性差以及血糖控製不佳的患者易齣現耐藥性。
목적：분석2형당뇨병（T2DM）합병폐결핵환자산생내약성적상관위험인소。방법：선취248례아원치료적결핵병환자，의거시부합병T2DM분위：연구조，98례，합병T2DM；대조조，150례，미합병T2 DM。수집량조적림상자료，통과회귀분석산생내약성적상관위험인소。결과：경응용단인소잡방검험，농촌거민、거주조건차、치료불지속、병정시간교장、의종성차、흡연、HbA1 c 치、BMI치、고지혈증등위상관위험인소，재경다인소비조건Logistic 회귀분석현시，치료불지속、병정초과1년、의종성차、흡연、HbA1 c치위발생내약적상관위험인소。결론：치료과정유중단、병정장、의종성차이급혈당공제불가적환자역출현내약성。
Objective:To analyze the risk factors associated with drug-resistant to patients with type 2 diabetes mellitus ( T2DM) and pulmonary tuberculosis by the regression analysis.Methods: The 248 pa-tients confirmed to pulmonary tuberculosis were chosen to retrospective analyze and divided into two groups , research group (98 cases, accomplished with T2DM) and control group (150 cases, non-accomplished with T2DM).The clinical data was collected to regression analysis, and the relative risk factors associated with drug-resistant were confirmed.Results: The factors of residence in rural areas, poor residence condition, treatment interruptions, long course of diseases, poor treatment compliance, smoking, HbA1c score, BMI score and hyperlipidemia were confirmed by the single factor chi-square test .Then the factors of treatment interruptions, long course of diseases, poor treatment compliance, smoking, HbA1c score were confirmed to risk factors associated with drug-resistant by multiple Logistic regression analysis .Conclusions: The pa-tients with the treatment interruptions, long course of diseases, poor treatment compliance, HbA1c score were been confirmed to produce drug resistance .
