CAJ | 학술논문

优选大黄中大黄酸的提取工艺。以乙醇浓度，料液比，提取时间为自变量，大黄酸含量为因变量，通过对自变量各水平的多元线性回归及二项式拟合，用星点设计一响应面法优选大黄的提取工艺。最佳工艺条件为乙醇浓度82．84％，料液比1：15．04，提取时间2．73h，在此最佳条件下，大黄中大黄酸含量的最大估计值为2．04mg·g^（-1）。优选得到的大黄中大黄酸提取工艺，方法简便。以此条件进行提取，可得到较高的大黄酸含量。
우선대황중대황산적제취공예。이을순농도，료액비，제취시간위자변량，대황산함량위인변량，통과대자변량각수평적다원선성회귀급이항식의합，용성점설계일향응면법우선대황적제취공예。최가공예조건위을순농도82．84％，료액비1：15．04，제취시간2．73h，재차최가조건하，대황중대황산함량적최대고계치위2．04mg·g^（-1）。우선득도적대황중대황산제취공예，방법간편。이차조건진행제취，가득도교고적대황산함량。
To optimize the extraction technology of rhein from rhubarb, the independent variables were ethanol concentration,liquidmaterial ratio and extraction time,the dependent variable was extraction rate of rhein. Linear or nonlinear mathematic models were used to estimate the relationship between independent and dependent variables. Central composite design and response surface methodology were used to optimize the process of extraction. The prediction was carried out through comparing the observed and predicted values. The optimum technological parameters were as follows: ethanol concentration 82.64% ,liquid-material ratio of 1:15.04 and extraction time 2.73 h. The highest extraction rate of essential oil was 2.04 mg .g-1 which was agreed with model predictions.The extraction technology was simple, reliable and highly predictive.