CAJ | 학술논문

1例72岁男性患者,因脑梗死后出现脑卒中后抑郁口服氟西汀(20 mg/d) 24个月.用药18个月后突然发生全身震颤,无其他伴发症状,ld后自行缓解,不遗留任何不适.用药23个月时又出现2次相似的全身震颤发作.体格检查和实验室检查未见明显异常,脑电图检查除外痫性发作和特发性震颤,考虑为氟西汀所致疑似5-羟色胺综合征.停用氟西汀后患者未再出现震颤.
1례72세남성환자,인뇌경사후출현뇌졸중후억욱구복불서정(20 mg/d) 24개월.용약18개월후돌연발생전신진전,무기타반발증상,ld후자행완해,불유류임하불괄.용약23개월시우출현2차상사적전신진전발작.체격검사화실험실검사미견명현이상,뇌전도검사제외간성발작화특발성진전,고필위불서정소치의사5-간색알종합정.정용불서정후환자미재출현진전.
A 72-year-old male received fluoxetine 20 mg daily for 24 months for post-stroke depression (PSD) due to cerebral infarction.After eighteen months of treatment,the patient developed synclonus tremens suddenly but without other complicated syndromes.The patient's condition improved spontaneously on the next day and did not leave any discomfort.After twenty-three months of treatment,the patient developed similar synclonus tremens two times again.The results of physical and laboratory examinations showed no obvious abnormality.The result of electrocardiogram examination eliminated the seizures and essential tremor.It was considered the suspected 5-serotonin syndrome induced by fluoxetine.Fluoxetine was stopped and the patient had no recurrence of synclonus tremens.