中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2013年
35期
152-153,154
,共3页
铜绿假单胞菌%医院感染%药物敏感试验%抗菌药物
銅綠假單胞菌%醫院感染%藥物敏感試驗%抗菌藥物
동록가단포균%의원감염%약물민감시험%항균약물
Pseudomonas aeruginosa%The hospital infection%Drug sensitive test%Antibacterial drugs
目的：了解铜绿假单胞菌（PAE）的临床感染分布及耐药现状，为预防和控制医院感染及合理用药提供依据。方法：采用常规方法对本院细菌室收集的临床标本进行菌株鉴定及药敏试验。结果：2009年1月-2012年12月间共分离出98株铜绿假单胞菌，标本来源以痰为主占73.5％（72/98），科室分布以内科系统（含重症监护病房）最多，占71.4％（70/98）。对磺胺甲恶唑/甲氧苄啶、头孢曲松、左氧氟沙星、庆大霉素、环丙沙星、妥布霉素等多种抗生素的耐药率均较高，分别为90.8％、66.3%、52.0%、51.0%、50.0%、44.9%。结论：铜绿假单胞菌是医院内感染的主要病原菌之一，随着分离率和耐药性的上升，应做好医院感染控制和抗菌药物分级管理工作，加强细菌培养及药物敏感试验，根据结果合理选用抗菌药物，减少或防止耐药菌株的产生或播散。
目的：瞭解銅綠假單胞菌（PAE）的臨床感染分佈及耐藥現狀，為預防和控製醫院感染及閤理用藥提供依據。方法：採用常規方法對本院細菌室收集的臨床標本進行菌株鑒定及藥敏試驗。結果：2009年1月-2012年12月間共分離齣98株銅綠假單胞菌，標本來源以痰為主佔73.5％（72/98），科室分佈以內科繫統（含重癥鑑護病房）最多，佔71.4％（70/98）。對磺胺甲噁唑/甲氧芐啶、頭孢麯鬆、左氧氟沙星、慶大黴素、環丙沙星、妥佈黴素等多種抗生素的耐藥率均較高，分彆為90.8％、66.3%、52.0%、51.0%、50.0%、44.9%。結論：銅綠假單胞菌是醫院內感染的主要病原菌之一，隨著分離率和耐藥性的上升，應做好醫院感染控製和抗菌藥物分級管理工作，加彊細菌培養及藥物敏感試驗，根據結果閤理選用抗菌藥物，減少或防止耐藥菌株的產生或播散。
목적：료해동록가단포균（PAE）적림상감염분포급내약현상，위예방화공제의원감염급합리용약제공의거。방법：채용상규방법대본원세균실수집적림상표본진행균주감정급약민시험。결과：2009년1월-2012년12월간공분리출98주동록가단포균，표본래원이담위주점73.5％（72/98），과실분포이내과계통（함중증감호병방）최다，점71.4％（70/98）。대광알갑악서/갑양변정、두포곡송、좌양불사성、경대매소、배병사성、타포매소등다충항생소적내약솔균교고，분별위90.8％、66.3%、52.0%、51.0%、50.0%、44.9%。결론：동록가단포균시의원내감염적주요병원균지일，수착분리솔화내약성적상승，응주호의원감염공제화항균약물분급관리공작，가강세균배양급약물민감시험，근거결과합리선용항균약물，감소혹방지내약균주적산생혹파산。
Objective:To understand Pseudomonas aeruginosa( PAE )infection clinical distribution and drug resistance situation.To provide basis for the prevention and control of hospital infection and rational drug use. Method:Strain identification and drug sensitive test of clinical specimens collected in our bacteria chamber were done by conventional method.Result:98 strains were separated between the pseudomonas aeruginosa from January 2009 to December 2012, specimens were from sputum accounted for 73.5%(72/98).Distribution of departments in Department of internal medicine(ICU system containing)the most,accounting for 71.4%(70/98).Resistance to sulfamethoxazole/trimethoprim variable ceftazidime,ceftriaxone,levofloxacin, ciprofloxacin,gentamicin,tobramycin and multiple antibiotic resistance rate were higher,respectively,90.8%,66.3%,52%,51%,50%,44.9%. Conclusion:Pseudomonas aeruginosa nosocomial infection is one of the main pathogenic bacteria,along with the separation rate and resistance, the rise of the hospital infection control should be done and antimicrobial drug classification management work,strengthens the bacterial culture and drug sensitive test,according to the result is reasonable to choose antimicrobial agents,to reduce or prevent drug-resistant strain generation or broadcast.
