CAJ | 학술논문

目的：探索在IVF/ICSI-ET中，胚胎移植第5天血清孕酮-雌激素比值对体外受精-胚胎移植妊娠结局的预测价值。方法收集接受IVF-ET长方案促排卵方案进行体外受精（IVF）/卵泡浆内单精子显微注射（ICSI）的患者移植周期资料进行分析，根据移植后妊娠结局分为妊娠组（300例，包括宫内活胎及妊娠结局不良者）及未妊娠组（380组），于移植第5天取血查血清雌二醇（E2）和孕激素（P）。结果妊娠组移植第5天的E2、 P、 P/E2分别为648.3±309.4、90.6±61.8、159.4±106.7，明显低于未妊娠组， P＜0.05。结论移植第5天恰当的雌孕激素比例与移植的妊娠结局有关。
목적：탐색재IVF/ICSI-ET중，배태이식제5천혈청잉동-자격소비치대체외수정-배태이식임신결국적예측개치。방법수집접수IVF-ET장방안촉배란방안진행체외수정（IVF）/란포장내단정자현미주사（ICSI）적환자이식주기자료진행분석，근거이식후임신결국분위임신조（300례，포괄궁내활태급임신결국불량자）급미임신조（380조），우이식제5천취혈사혈청자이순（E2）화잉격소（P）。결과임신조이식제5천적E2、 P、 P/E2분별위648.3±309.4、90.6±61.8、159.4±106.7，명현저우미임신조， P＜0.05。결론이식제5천흡당적자잉격소비례여이식적임신결국유관。
Objective To investigate the predictive value of serum progesterone and estrogen ratio ( SP/E2 ) to pregnancy out-come of in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI-ET) on the fifth day after embryo transfer.Method By col-lecting and analyzing the transfer cycle data of patients receiving IVF-ET long protocol ovulation induction in vitro fertilization ( IVF) /intracytoplasmic sperm injection (ICSI).According to the outcome of pregnancy after transfer, these data were divided into pregnant group (300 cases, including live intrauterine fetal and adverse pregnancy outcomes) and non pregnancy group (380 cases).Then blood was taken and serum levels of estradiol (E2) and progesterone (P) were checked on the fifth day after transfer.Results On the fifth day of transfer, the values of E2, P, P/E2 of pregnancy group were 648.3±309.4, 90.6±61.8, 159.4±106.7, which were significantly lower than those of the non pregnant group, P<0.05.Conclusion On the fifth day after transfer, appropriate proportion of estrogen and progesterone is associated with the pregnancy outcome of transfer.