CAJ | 학술논문

目的综述当前用于循证航天医学证据系统评价中Meta-分析技术的发展与应用,总结其应用特点与效果,并根据航天医学研究及航天实施医学的特点提出实施Meta-分析时应注意的问题. 资料来源与选择国内外相关领域的学术论著及综述. 资料引用相关文献26篇.资料综合 Meta-分析是建立在随机对照试验的基础上,进行科学的评估和统计处理,其多项研究的汇总统计量或效应尺度可为进一步研究提供可靠的文献数据,也可为科学决策提供可靠的参考依据.有效证据是实施循证航天医学“三要素”之一,而Meta-分析技术是获得有效证据的重要途径,做好Meta-分析,对实施循证航天医学具有重要意义. 结论最少选择性偏倚、样本量偏倚和统计性偏倚的系统评价是产生循证航天医学最佳证据的重要途经,而在开展系统评价时要靠Meta-分析技术来实现,如何根据航天医学的特点做好Meta-分析尚须进行深入研究.
목적 종술당전용우순증항천의학증거계통평개중Meta-분석기술적발전여응용,총결기응용특점여효과,병근거항천의학연구급항천실시의학적특점제출실시Meta-분석시응주의적문제. 자료래원여선택 국내외상관영역적학술론저급종술. 자료인용 상관문헌26편.자료종합 Meta-분석시건립재수궤대조시험적기출상,진행과학적평고화통계처리,기다항연구적회총통계량혹효응척도가위진일보연구제공가고적문헌수거,야가위과학결책제공가고적삼고의거.유효증거시실시순증항천의학“삼요소”지일,이Meta-분석기술시획득유효증거적중요도경,주호Meta-분석,대실시순증항천의학구유중요의의. 결론 최소선택성편의、양본량편의화통계성편의적계통평개시산생순증항천의학최가증거적중요도경,이재개전계통평개시요고Meta-분석기술래실현,여하근거항천의학적특점주호Meta-분석상수진행심입연구.
Objective To review the current development and application of meta-analysis in systematic review of evidence-based space medicine,to describe the characteristics and effects of the meta-analysis,and to put forward the questions that should be cared to the research work of space medicine and space operational medicine.Literature resource and selection The professional reports,articles and books that published at home and abroad.Literature quotation Twenty-six papers,study reports and monographs were cited.Literature synthesis Meta-analysis could scientifically summarize and assemble the results of the studies based on the randomized control trials.The overall statistics or effect magnitude could give us the evidence for scientifically making decisions or providing effective references for further studies.Best evidence played one of the " three main elements"of evidence-base space medicine and meta-analysis was the important method to obtain the best evidence.Paper also discussed how we applied the meta-analysis better.Conclusion The best evidence of space medicine comes from the systematic review with the least bias of material selection,sample size and statistics.Meta-analysis would enable a better systematic review even its applications still to be further studied to fit the characteristics of space medicine.