CAJ | 학술논문

目的：利用血管回声跟踪（ ET）技术评价头颈部肿瘤患者放疗后颈总动脉弹性。方法：分别纳入38例头颈部肿瘤放疗患者（观察组）与38例头颈部肿瘤未接受放疗患者（对照组），用ET技术检测患者颈总动脉弹性指标[包括僵硬系数（β）、压力应变弹性系数（Ep）、顺应性（AC）、扩大指数（AI）、脉搏波传播速度（PWVβ）]和颈总动脉内-中膜厚度（ IMT），比较两组患者颈总动脉弹性指标和IMT的差异。结果：观察组患者左右两侧颈总动脉β、Ep、AI和PWVβ高于对照组，差异有统计学意义（ t＝3．956和4．215，10．242和8．831，4．382和3．442，3．761和4．679，P＜0．001）；左右两侧颈总动脉AC低于对照组，差异有统计学意义（t＝4．671和4．962，P＜0．001）。两组患者IMT比较差异无统计学意义（P＞0．05）。结论：ET技术可早期发现头颈部肿瘤放疗患者颈动脉损伤，为临床干预提供了依据。
목적：이용혈관회성근종（ ET）기술평개두경부종류환자방료후경총동맥탄성。방법：분별납입38례두경부종류방료환자（관찰조）여38례두경부종류미접수방료환자（대조조），용ET기술검측환자경총동맥탄성지표[포괄강경계수（β）、압력응변탄성계수（Ep）、순응성（AC）、확대지수（AI）、맥박파전파속도（PWVβ）]화경총동맥내-중막후도（ IMT），비교량조환자경총동맥탄성지표화IMT적차이。결과：관찰조환자좌우량측경총동맥β、Ep、AI화PWVβ고우대조조，차이유통계학의의（ t＝3．956화4．215，10．242화8．831，4．382화3．442，3．761화4．679，P＜0．001）；좌우량측경총동맥AC저우대조조，차이유통계학의의（t＝4．671화4．962，P＜0．001）。량조환자IMT비교차이무통계학의의（P＞0．05）。결론：ET기술가조기발현두경부종류방료환자경동맥손상，위림상간예제공료의거。
Aim:To assess the effect of echo-tracking technology in evaluating the common carotid artery elasticity in patients with head and neck tumor after radiotherapy .Methods: A total of 76 cases were allocated into two groups: the therapy group including 38 patients with head and neck tumor after radiotherapy and the control group including 38 patients with head and neck tumor without radiotherapy .Echo-tracking technology was used to evaluate the carotid elastic indexes [the stiffness parameter(β), pressure-strain elastic modulus(Ep), arterial compliance(AC), augment index(AI), and pulse wave conducting velocity ( PWVβ) ] and carotid artery intima-media thickness ( IMT) .Results:β,Ep,AI,and PWVβin the therapy group were significantly higher than those in control group on both sides of the common carotid artery ( t=3.956 and 4.215,10.242 and 8.831,4.382 and 3.442,3.761 and 4.679,P<0.001).Compared with control group , the therapy group had lower AC(t=4.671 and 4.962, P<0.001).There was no difference in IMT between the 2 groups(P>0.05).Conclusion:Echo-tracking technique is a feasible way to discover the early radiation damage of carotid artery in patients with head and neck tumor after radiotherapy and provide basis for clinical treatment .