CAJ | 학술논문

目的：综述近年来口服结肠释药系统临床和药学研究动态，为今后在此领域的研究和临床应用提供参考。方法：通过对国内外相关文献资料的整理，对比和分析，总结口服结肠释药系统制剂进展和临床应用的发展方向。结果结论：口服结肠释药系统是通过口服给药，在结肠处定位释放药物的靶向制剂。此类制剂以其靶向释药方式和独特的临床使用价值，越来越广泛地引起了临床医生的关注，同时也成为药学研究领域的一大热点。
목적：종술근년래구복결장석약계통림상화약학연구동태，위금후재차영역적연구화림상응용제공삼고。방법：통과대국내외상관문헌자료적정리，대비화분석，총결구복결장석약계통제제진전화림상응용적발전방향。결과결론：구복결장석약계통시통과구복급약，재결장처정위석방약물적파향제제。차류제제이기파향석약방식화독특적림상사용개치，월래월엄범지인기료림상의생적관주，동시야성위약학연구영역적일대열점。
Objective: To review the novel approaches of oral colon targeted drug delivery system in pharmaceutical research and clinical applications. Methods: Related research literatures published recently were compared, analyzed and evaluated. The development and the future application of this drug delivery system were summarized. Results and Conclusion: Oral colon drug delivery system(OCDDS)is a target delivery pharmaceutical dosage form, which releases the drug exclusively in the colon. Due to the distinguished advantages and increasing clinical applications, OCDDS draw wide attention from clinicians and become a very active research field in pharmaceutics.