CAJ | 학술논문

目的：在单因素实验结果的基础上，采用星点设计-效应面法优选白藜芦醇的提取工艺条件。方法：用有机溶剂水浴浸提法提取虎杖中白藜芦醇，以白藜芦醇含量为评价指标，采用星点设计考察溶剂浓度、提取时间和溶剂用量对提取工艺的影响，效应面法优化提取工艺条件。结果：最佳工艺条件：乙醇浓度72.0%，提取温度50℃，提取2次，每次1.1 h，溶剂用量12.7倍，白藜芦醇含量理论最大值与实测值平均偏差为0.83%。结论：该优选工艺预测性良好，可为白藜芦醇提取的工业生产提供实验依据。
목적：재단인소실험결과적기출상，채용성점설계-효응면법우선백려호순적제취공예조건。방법：용유궤용제수욕침제법제취호장중백려호순，이백려호순함량위평개지표，채용성점설계고찰용제농도、제취시간화용제용량대제취공예적영향，효응면법우화제취공예조건。결과：최가공예조건：을순농도72.0%，제취온도50℃，제취2차，매차1.1 h，용제용량12.7배，백려호순함량이론최대치여실측치평균편차위0.83%。결론：해우선공예예측성량호，가위백려호순제취적공업생산제공실험의거。
This study was aimed to optimize the extraction process of resveratrol by central composite design (CCD) and response surface method (RSM), based on the result of single factor experiment. Resveratrol was extracted from Polygonum cuspidatum by water bath extraction of organic solvent. And content of resveratrol was taken as index in the investigation of solvent concentration effect, extraction time and solvent content on extraction process. The results showed that the optimum condition was 12.7 times amount of 72.0% ethanol and extract for 2 times under the temperature of 50℃, 1.1 h for each time; the average deviation between the maximum theoretical value and measured value was 0.83%. It was concluded that this extraction process was highly predictive, which provided experimental evidence for the industrial production of P. cuspidatum extraction.