世界科学技术-中医药现代化
世界科學技術-中醫藥現代化
세계과학기술-중의약현대화
WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
2014年
5期
1188-1192
,共5页
王莹%韩丽%郭志烨%刘李梅%张喻娟%杨明
王瑩%韓麗%郭誌燁%劉李梅%張喻娟%楊明
왕형%한려%곽지엽%류리매%장유연%양명
萎康胶囊%淫羊藿%银杏叶%正交试验%提取工艺
萎康膠囊%淫羊藿%銀杏葉%正交試驗%提取工藝
위강효낭%음양곽%은행협%정교시험%제취공예
Wei-Kang Capsule%Epimedium brevicornum%leaves of ginkgo biloba%orthogonal test%extraction technology
目的:优选中药复方制剂萎康胶囊的提取工艺。方法:采用正交试验法,以淫羊藿苷、总黄酮醇苷的含量以及干膏得率作为考察指标,对乙醇浓度、乙醇用量、提取时间、提取次数4个因素进行考察,并结合综合评价的方法优选出萎康胶囊的提取工艺。结果:最佳提取工艺:12倍量60%乙醇,回流提取3次,每次1h。结论:优选出的萎康胶囊提取工艺稳定可行、科学合理,可用于工业化大生产。
目的:優選中藥複方製劑萎康膠囊的提取工藝。方法:採用正交試驗法,以淫羊藿苷、總黃酮醇苷的含量以及榦膏得率作為攷察指標,對乙醇濃度、乙醇用量、提取時間、提取次數4箇因素進行攷察,併結閤綜閤評價的方法優選齣萎康膠囊的提取工藝。結果:最佳提取工藝:12倍量60%乙醇,迴流提取3次,每次1h。結論:優選齣的萎康膠囊提取工藝穩定可行、科學閤理,可用于工業化大生產。
목적:우선중약복방제제위강효낭적제취공예。방법:채용정교시험법,이음양곽감、총황동순감적함량이급간고득솔작위고찰지표,대을순농도、을순용량、제취시간、제취차수4개인소진행고찰,병결합종합평개적방법우선출위강효낭적제취공예。결과:최가제취공예:12배량60%을순,회류제취3차,매차1h。결론:우선출적위강효낭제취공예은정가행、과학합리,가용우공업화대생산。
This study was aimed to optimize the extraction technology of Wei-Kang (WK) Capsule. Orthogonal test and comprehensive evaluation were used to optimize the extraction process of compound preparation. The icarrin, to-tal ginkgo flavone glycosides and the dried decocting rates were used as index components for optimizing the effect of ethanol concentration, ethanol volume, extraction duration and extraction frequency. The results showed that the opti-mal ethanol extraction technology was adding 12 times of 60% ethanol and extract for 3 times with 1 h for each ex-traction time. It was concluded that the optimized extraction technology was stable, practical, scientific and reason-able, which can be used in the large-scale industrial production.