世界科学技术-中医药现代化
世界科學技術-中醫藥現代化
세계과학기술-중의약현대화
WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
2014年
5期
1182-1187
,共6页
王忠雷%杨丽燕%张小华
王忠雷%楊麗燕%張小華
왕충뢰%양려연%장소화
5,7,3',4'-O-四甲基槲皮素%制备工艺%单因素实验%正交试验
5,7,3',4'-O-四甲基槲皮素%製備工藝%單因素實驗%正交試驗
5,7,3',4'-O-사갑기곡피소%제비공예%단인소실험%정교시험
5,7,3',4'-O-tetramethylquercetin%preparation process%single factor test%orthogonal test
目的：优化5，7，3’，4’-O-四甲基槲皮素（TMQ）的制备工艺。方法：以5，7，3’，4’-O-四甲基芦丁为原料，采用单因素实验和正交试验对TMQ的制备工艺进行优化。结果：酸性水溶液法制备TMQ的最佳工艺条件为：乙醇浓度0，温度80℃，盐酸浓度0.50%，水解时间1.0 h。结论：该方法收率高、工艺简单、稳定可行。
目的：優化5，7，3’，4’-O-四甲基槲皮素（TMQ）的製備工藝。方法：以5，7，3’，4’-O-四甲基蘆丁為原料，採用單因素實驗和正交試驗對TMQ的製備工藝進行優化。結果：痠性水溶液法製備TMQ的最佳工藝條件為：乙醇濃度0，溫度80℃，鹽痠濃度0.50%，水解時間1.0 h。結論：該方法收率高、工藝簡單、穩定可行。
목적：우화5，7，3’，4’-O-사갑기곡피소（TMQ）적제비공예。방법：이5，7，3’，4’-O-사갑기호정위원료，채용단인소실험화정교시험대TMQ적제비공예진행우화。결과：산성수용액법제비TMQ적최가공예조건위：을순농도0，온도80℃，염산농도0.50%，수해시간1.0 h。결론：해방법수솔고、공예간단、은정가행。
This study was aimed to optimize optimum preparation process of 5,7,3',4'-O-tetramethylquercetin (TMQ). With 5,7,3',4'-O-tetramethylrutin as raw material, TMQ was prepared by acidic aqueous solution method. The preparation process of TMQ was optimized by single factor test and orthogonal test. The results showed that the optimum technology conditions were ethanol concentration at 0, temperature at 80℃, hydrochloric acid concentration at 0.50%, and the hydrolysis time for 1.0 h. It was concluded that the optimum preparation process had the charac-teristics of high yield, simple process, stable and feasible.
