世界科学技术-中医药现代化
世界科學技術-中醫藥現代化
세계과학기술-중의약현대화
WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
2014年
5期
966-971
,共6页
袁梽漪%卢希%雷帆%柴玉爽%冯天师%姜敬非%赵爽%王欣佩%李慧玉%邢东明%杜力军
袁梽漪%盧希%雷帆%柴玉爽%馮天師%薑敬非%趙爽%王訢珮%李慧玉%邢東明%杜力軍
원지의%로희%뢰범%시옥상%풍천사%강경비%조상%왕흔패%리혜옥%형동명%두력군
菠萝叶%药用价值%生殖毒性%小鼠
菠蘿葉%藥用價值%生殖毒性%小鼠
파라협%약용개치%생식독성%소서
Pineapple leaves%medical value%reproductive toxicity%mice
目的：对菠萝叶小鼠的一般生殖毒性进行研究，有助于更好的评价该植物的药用价值。方法：分别灌胃给予成年雄性和雌性小鼠菠萝叶，然后合笼进行交配。对于交配成功的雌鼠继续饲养。分别对孕鼠的妊娠、胎鼠的发育及生产的子代小鼠的情况进行实验观察。结果：菠萝叶除了大剂量（4 g·kg-1）对亲本雄性鼠体重有一定降低外，对其它各项指标均无明显影响。对孕鼠及其子代小鼠均未见有明显影响。结论：提示菠萝叶对小鼠一般生殖功能无明显毒性。
目的：對菠蘿葉小鼠的一般生殖毒性進行研究，有助于更好的評價該植物的藥用價值。方法：分彆灌胃給予成年雄性和雌性小鼠菠蘿葉，然後閤籠進行交配。對于交配成功的雌鼠繼續飼養。分彆對孕鼠的妊娠、胎鼠的髮育及生產的子代小鼠的情況進行實驗觀察。結果：菠蘿葉除瞭大劑量（4 g·kg-1）對親本雄性鼠體重有一定降低外，對其它各項指標均無明顯影響。對孕鼠及其子代小鼠均未見有明顯影響。結論：提示菠蘿葉對小鼠一般生殖功能無明顯毒性。
목적：대파라협소서적일반생식독성진행연구，유조우경호적평개해식물적약용개치。방법：분별관위급여성년웅성화자성소서파라협，연후합롱진행교배。대우교배성공적자서계속사양。분별대잉서적임신、태서적발육급생산적자대소서적정황진행실험관찰。결과：파라협제료대제량（4 g·kg-1）대친본웅성서체중유일정강저외，대기타각항지표균무명현영향。대잉서급기자대소서균미견유명현영향。결론：제시파라협대소서일반생식공능무명현독성。
This article was aimed to study the general reproductive toxicity in mice in order to give a better evalua-tion of the medicinal plant of pineapple leaves (A nanas comasus L). Adult male and female mice were orally admin-istered with pineapple leaves. And then, each of the male and female mice was put together in one cage for mating. The mating success females were fed continuously. The experimental observation was conducted in pregnancy, fetal development, as well as the offspring of mice. The results showed that in addition to a large dose of pineapple leaves (4 g·kg-1) of the parental male rats having a lower body weight, pineapple leaves did not significantly affect on other parameters. There were no significant effects on pregnant mice and their offspring of mice. It was concluded that the pineapple leaves did not influence the general reproductive function of mice apparently.
