CAJ | 학술논문

目的：观察大肠癌围手术期患者中医证候分布及动态变化规律，为中医药干预提供证候学依据。方法对228例大肠癌手术患者进行临床调查，观察手术前后临床症状、舌象、中医辨证及证候变化。结果大肠癌患者术前以气血瘀滞证（34.2%）和湿热蕴结证（28.9%）两类实证为主；术后早期（术后1周）虚性证候明显增加，主要为气血两虚证（17.1%）；术后中期（术后1个月）呈现虚实夹杂之象；术后晚期（术后3个月）虚证比例逐渐降低；结论大肠癌患者围手术期中医证候演变呈现一定规律，大肠癌围手术期的中医药治疗可遵循这一规律。
목적：관찰대장암위수술기환자중의증후분포급동태변화규률，위중의약간예제공증후학의거。방법대228례대장암수술환자진행림상조사，관찰수술전후림상증상、설상、중의변증급증후변화。결과대장암환자술전이기혈어체증（34.2%）화습열온결증（28.9%）량류실증위주；술후조기（술후1주）허성증후명현증가，주요위기혈량허증（17.1%）；술후중기（술후1개월）정현허실협잡지상；술후만기（술후3개월）허증비례축점강저；결론대장암환자위수술기중의증후연변정현일정규률，대장암위수술기적중의약치료가준순저일규률。
Objective To observe the changes of TCM syndromes of colorectal cancer patients before and after surgery,in order to guide the TCM treatment. Methods Two hundred and twenty-eight patients with colorectal cancer were enrolled. Their signs and symptoms,tongue picture,and differentiated TCM syndromes before and after surgery were compared. Results The preoperative TCM syndromes were characterized by excess such as qi stagna-tion and blood stasis (34.2%) and accumulation of damp-heat (28.9%). In the early stage after surgery (no more than one week),the deficient syndromes gradually increased,with the syndrome of qi-blood deficiency accounting for 17.1%;in the middle stage after surgery (one month),a phenomenon of combined excess and deficiency syn-dromes presented;in the later stage of postoperation(3 months),the deficient syndromes decreased. Conclusion The evolution of perioperative TCM syndromes in patients with colorectal cancer may follow certain patterns. This may be of value in guidance of adjuvant TCM treatments of colorectal cancer.