中华眼科杂志
中華眼科雜誌
중화안과잡지
Chinese Journal of Ophthalmology
2014年
6期
421-425
,共5页
冯雪艳%叶存喜%牟明春%陈海婷
馮雪豔%葉存喜%牟明春%陳海婷
풍설염%협존희%모명춘%진해정
一过性黑朦%颈动脉狭窄%眼动脉%视网膜动脉%血流动力学%颈动脉%超声检查,多普勒,彩色
一過性黑朦%頸動脈狹窄%眼動脈%視網膜動脈%血流動力學%頸動脈%超聲檢查,多普勒,綵色
일과성흑몽%경동맥협착%안동맥%시망막동맥%혈류동역학%경동맥%초성검사,다보륵,채색
Amaurosis fugax%Carotid stenosis%Ophthalmic artery%Retinal artery%Hemodynamics%Carotid arteries%Ultrasonography,doppler,color
目的:探讨一过性黑朦与颈动脉狭窄的相关性及其球后血管血流动力学变化规律。方法病例对照研究。收集2011年5月至2012年12月在沧州市中心医院眼科就诊的32例(32只眼)一过性黑朦患者的临床资料(一过性黑朦组),男性19例,女性13例,年龄50~80岁,平均年龄(64.31±8.15)岁。并收集同期眼科门诊收治的30例非视网膜缺血性疾病患者的临床资料作为对照组。两组患者均行眼动脉、视网膜中央动脉及颈动脉的彩色超声检查,检测其球后血管的收缩期峰值流速(PSV)、舒张末期流速(EDV)、阻力指数(RI)及颈动脉狭窄程度、颈动脉斑块部位及类型。分别采用卡方检验和 t 检验对检测结果进行统计学分析。结果一过性黑朦组患者眼动脉 PSV [(25.95±2.45)cm/s]较对照组PSV[(27.53±1.41) cm/s]流速减低(t=3.087, P=0.003)、EDV [(6.01±0.87) cm/s]较对照组EDV[(6.89±0.56) cm/s]降低(t=0.712, P=0.048),RI值与对照组差异无统计学意义(t =0.188, P =0.852)。一过性黑朦组其视网膜中央动脉 PSV[(7.13±0.96)cm/s]较对照组 PSV[(8.23±0.92) cm/s]流速减低(t =4.648, P =0.000),EDV[(1.78±0.26)cm/s]较对照组EDV[(2.13±0.29)cm/s]流速降低(t=4.976, P=0.000),RI值与对照组比较,差异无统计学意义(t=0.180, P=0.855)。一过性黑朦组颈动脉中重度狭窄检出率(59.4%)明显高于对照组(6.7%)(χ2=19.205, P=0.000)。结论一过性黑朦患者的视网膜中央动脉和眼动脉的血流速度明显降低,而阻力正常,而且约60%的患者存在中重度的颈动脉狭窄,提示颈动脉狭窄与一过性黑朦的发病密切相关。(中华眼科杂志,2014,50:421-425)
目的:探討一過性黑朦與頸動脈狹窄的相關性及其毬後血管血流動力學變化規律。方法病例對照研究。收集2011年5月至2012年12月在滄州市中心醫院眼科就診的32例(32隻眼)一過性黑朦患者的臨床資料(一過性黑朦組),男性19例,女性13例,年齡50~80歲,平均年齡(64.31±8.15)歲。併收集同期眼科門診收治的30例非視網膜缺血性疾病患者的臨床資料作為對照組。兩組患者均行眼動脈、視網膜中央動脈及頸動脈的綵色超聲檢查,檢測其毬後血管的收縮期峰值流速(PSV)、舒張末期流速(EDV)、阻力指數(RI)及頸動脈狹窄程度、頸動脈斑塊部位及類型。分彆採用卡方檢驗和 t 檢驗對檢測結果進行統計學分析。結果一過性黑朦組患者眼動脈 PSV [(25.95±2.45)cm/s]較對照組PSV[(27.53±1.41) cm/s]流速減低(t=3.087, P=0.003)、EDV [(6.01±0.87) cm/s]較對照組EDV[(6.89±0.56) cm/s]降低(t=0.712, P=0.048),RI值與對照組差異無統計學意義(t =0.188, P =0.852)。一過性黑朦組其視網膜中央動脈 PSV[(7.13±0.96)cm/s]較對照組 PSV[(8.23±0.92) cm/s]流速減低(t =4.648, P =0.000),EDV[(1.78±0.26)cm/s]較對照組EDV[(2.13±0.29)cm/s]流速降低(t=4.976, P=0.000),RI值與對照組比較,差異無統計學意義(t=0.180, P=0.855)。一過性黑朦組頸動脈中重度狹窄檢齣率(59.4%)明顯高于對照組(6.7%)(χ2=19.205, P=0.000)。結論一過性黑朦患者的視網膜中央動脈和眼動脈的血流速度明顯降低,而阻力正常,而且約60%的患者存在中重度的頸動脈狹窄,提示頸動脈狹窄與一過性黑朦的髮病密切相關。(中華眼科雜誌,2014,50:421-425)
목적:탐토일과성흑몽여경동맥협착적상관성급기구후혈관혈류동역학변화규률。방법병례대조연구。수집2011년5월지2012년12월재창주시중심의원안과취진적32례(32지안)일과성흑몽환자적림상자료(일과성흑몽조),남성19례,녀성13례,년령50~80세,평균년령(64.31±8.15)세。병수집동기안과문진수치적30례비시망막결혈성질병환자적림상자료작위대조조。량조환자균행안동맥、시망막중앙동맥급경동맥적채색초성검사,검측기구후혈관적수축기봉치류속(PSV)、서장말기류속(EDV)、조력지수(RI)급경동맥협착정도、경동맥반괴부위급류형。분별채용잡방검험화 t 검험대검측결과진행통계학분석。결과일과성흑몽조환자안동맥 PSV [(25.95±2.45)cm/s]교대조조PSV[(27.53±1.41) cm/s]류속감저(t=3.087, P=0.003)、EDV [(6.01±0.87) cm/s]교대조조EDV[(6.89±0.56) cm/s]강저(t=0.712, P=0.048),RI치여대조조차이무통계학의의(t =0.188, P =0.852)。일과성흑몽조기시망막중앙동맥 PSV[(7.13±0.96)cm/s]교대조조 PSV[(8.23±0.92) cm/s]류속감저(t =4.648, P =0.000),EDV[(1.78±0.26)cm/s]교대조조EDV[(2.13±0.29)cm/s]류속강저(t=4.976, P=0.000),RI치여대조조비교,차이무통계학의의(t=0.180, P=0.855)。일과성흑몽조경동맥중중도협착검출솔(59.4%)명현고우대조조(6.7%)(χ2=19.205, P=0.000)。결론일과성흑몽환자적시망막중앙동맥화안동맥적혈류속도명현강저,이조력정상,이차약60%적환자존재중중도적경동맥협착,제시경동맥협착여일과성흑몽적발병밀절상관。(중화안과잡지,2014,50:421-425)
Objective To investigate the correlation of amaurosis fugax and carotid stenosis as well as posterior ocular blood vessel hemodynamic changes.Methods Case series studies.32 patients (19 men and 13 women whose age were 50 to 80 years old and average age was 64.31 ±8.15) who were diagnosed as amaurosis fugax with 32 eyes were enrolled from 2011.5-2012.12.During the same period 30 cases without posterior ocular ischemic diseases were collected as the control group.Their ophthalmic artery , central retinal artery and carotid artery were examinated by color Doppler ultrasound , to detect vascular peak systolic velocity, end diastolic velocity, resistance index, the degree of carotid stenosis, carotid artery plaque area and type.All data were analyzed by chi-square test and t-test.Results PSV(25.95 ±2.45) cm/s,EDV (6.01 ±0.87) cm/s of the ophthalmic artery in AmF group were lower compared with the control group [PSV:(27.53 ±1.41) cm/s, EDV: (6.89 ±0.56) cm/s].The differences were statistically significant (t=3.087, 0.712, P=0.003, 0.048).There was no statistical difference of RI between AmF and the control group (t=0.188, P=0.852) .PSV(7.13 ±0.96) cm/s,EDV(1.78 ±0.26) cm/s of the central retinal artery in AmF group were lower compared with the control group [PSV:(8.23 ±0.92) cm/s, EDV:(2.13 ±0.29) cm/s].The differences were statistically significant (t=4.648, 4.976, P=0.000, 0.000).There was no statistical difference of RI between AmF and the control group ( t=0.180, P=0.855).Detection rate of carotid artery moderately and severe stenosis ( 59.4%) was significantly higher compared with the control group (6.7%).The difference was statistically significant (χ2 =19.205, P =0.000).Conclusions The blood flow velocity of ophthalmic artery and central retinal artery in amaurosis fugax patients reduced significantly , while the resistance was normal.About 60%of the patients had carotid artery moderately and severe stenosis.There was significant correlation between amaurosis fugax and carotid artery stenosis.