CAJ | 학술논문

回顾性分析186例上消化道出血期间痛风急性发作患者临床资料，男女之比为1.7∶1，吸烟、饮酒者占66.1％（123/186），有基础疾病的占62.4％（116/186），所有患者均有关节红肿痛及血尿酸升高。接受胃镜检查166例，行胃镜下治疗88例。痛风急性发作时治疗上加用塞来昔布及地塞米松可控制痛风症状，未诱发或加重消化道出血。提示消化道出血期间痛风急性发作时使用选择性环氧合酶-2抑制剂及激素在一定程度上是相对安全的。
회고성분석186례상소화도출혈기간통풍급성발작환자림상자료，남녀지비위1.7∶1，흡연、음주자점66.1％（123/186），유기출질병적점62.4％（116/186），소유환자균유관절홍종통급혈뇨산승고。접수위경검사166례，행위경하치료88례。통풍급성발작시치료상가용새래석포급지새미송가공제통풍증상，미유발혹가중소화도출혈。제시소화도출혈기간통풍급성발작시사용선택성배양합매-2억제제급격소재일정정도상시상대안전적。
The clinical data of 186 patients with acute gout attack during upper gastrointestinal bleeding were analyzed retrospectively.The ratio of male to female was 1.7∶1, smokers and alcohol drinkers accounted for 66.1% ( 123/186 ) and 62.4% ( 116/186 ) of patients were had underlying diseases.All patients had different degree of joint painful and fever , the blood uric acid levels were higher.Gastroscopic examinations were performed in 166 patients , of whom 88 cases received endoscopic intervention.The symptoms of gout were improved after treatment with dexamethasone and celecoxib ; and the medication did not induce or increase gastrointestinal bleeding.