中国保健营养(上旬刊)
中國保健營養(上旬刊)
중국보건영양(상순간)
China Health Care & Nutrition
2014年
6期
3108-3108,3109
,共2页
低分子肝素%新生儿%弥散性%血管内凝血%疗效
低分子肝素%新生兒%瀰散性%血管內凝血%療效
저분자간소%신생인%미산성%혈관내응혈%료효
Low molecular weight heparin%Newborn%Diffuse%Intravascular coagulation%Curative effect
目的:观察低分子肝素治疗新生儿弥散性血管内凝血( disseminated intravascular coagulation ,DIC)的疗效。方法对32例确诊的 DIC患者在积极治疗基础疾病的同时,予低分子肝素100IU/Kg皮下注射,2次/d,隔12h1次.观察出血状况及凝血酶原时间( PT)、活化部分凝血活酶时间( APTT)、纤维蛋白原(Fbg)、D-二聚体、纤维蛋白(原)降解产物(FDP)、3P试验、血小板(Plt)等指标。结果治愈28例,显效2例,无效2例,总有效率93.7%;PT、Fbg、Plt、D-二聚体、FDP和3P试验治疗后较治疗前有明显改善(P<0.05),无一例应用低分子肝素后出血表现加重。结论低分子肝素治疗 DIC 安全有效,副作用小。
目的:觀察低分子肝素治療新生兒瀰散性血管內凝血( disseminated intravascular coagulation ,DIC)的療效。方法對32例確診的 DIC患者在積極治療基礎疾病的同時,予低分子肝素100IU/Kg皮下註射,2次/d,隔12h1次.觀察齣血狀況及凝血酶原時間( PT)、活化部分凝血活酶時間( APTT)、纖維蛋白原(Fbg)、D-二聚體、纖維蛋白(原)降解產物(FDP)、3P試驗、血小闆(Plt)等指標。結果治愈28例,顯效2例,無效2例,總有效率93.7%;PT、Fbg、Plt、D-二聚體、FDP和3P試驗治療後較治療前有明顯改善(P<0.05),無一例應用低分子肝素後齣血錶現加重。結論低分子肝素治療 DIC 安全有效,副作用小。
목적:관찰저분자간소치료신생인미산성혈관내응혈( disseminated intravascular coagulation ,DIC)적료효。방법대32례학진적 DIC환자재적겁치료기출질병적동시,여저분자간소100IU/Kg피하주사,2차/d,격12h1차.관찰출혈상황급응혈매원시간( PT)、활화부분응혈활매시간( APTT)、섬유단백원(Fbg)、D-이취체、섬유단백(원)강해산물(FDP)、3P시험、혈소판(Plt)등지표。결과치유28례,현효2례,무효2례,총유효솔93.7%;PT、Fbg、Plt、D-이취체、FDP화3P시험치료후교치료전유명현개선(P<0.05),무일례응용저분자간소후출혈표현가중。결론저분자간소치료 DIC 안전유효,부작용소。
Objective To observe the effects of low molecular heparin in the treatment of neonatal disseminated intravascular coagulation effect .Methods On 32 ca-ses of DIC patients in the active treatment of underlying diseases at the same time ,treated with low molecular weight heparin subcutaneous injection of 100IU/Kg,2 times/D,every 12h1 times.Status and prothrombin time of hemorrhage(PT),activated partial thromboplastin time(APTT),fibrinogen(Fbg),D-dimer,fibrinogen(former-ly)degradation products(FDP),3P test,platelet(Plt)and other indicators.Results 28 cases were cured,2 cases markedly effective,2 cases ineffective,the total efficiency of93.7%;PT,Fbg,Plt,D-two,FDPand3Pdimertestaftertreatmentthanbeforetreatmentsignificantlyimproved(P<0.05),andnocaseoftheapplicationoflowmo-lecular weight heparin after hemorrhage increased.Conclusion Low molecular weight heparin in the treatment of DIC is safe and effective,less side effect.