CAJ | 학술논문

目的：观察乌荞降糖颗粒对糖耐量减低（ IGT）患者血糖及血清胰岛素的影响。方法将100例IGT患者随机分为2组。对照组50例予运动治疗，治疗组50例在对照组治疗基础上应用乌荞降糖颗粒，2组均连续治疗6个月。观察2组治疗后转归情况，比较2组治疗前后空腹血糖（ FPG）、餐后2 h血糖（2 hPG）、糖化血红蛋白（ HbAlc）及空腹胰岛素（ FINS）变化。结果治疗组治疗后糖耐量正常率高于对照组（P＜0．05）。治疗组治疗后FPG、2 hPG、HbAlc及FINS均较本组治疗前降低（P＜0．05，P＜0．01）；对照组治疗后FPG、2 hPG及FINS均较本组治疗前降低（P＜0．05）；治疗组治疗后2 hPG、HbAlc及FINS均低于对照组（P＜0．05，P＜0．01）。结论乌荞降糖颗粒可有效改善糖耐量，降低IGT患者发生糖尿病的风险。
목적：관찰오교강당과립대당내량감저（ IGT）환자혈당급혈청이도소적영향。방법장100례IGT환자수궤분위2조。대조조50례여운동치료，치료조50례재대조조치료기출상응용오교강당과립，2조균련속치료6개월。관찰2조치료후전귀정황，비교2조치료전후공복혈당（ FPG）、찬후2 h혈당（2 hPG）、당화혈홍단백（ HbAlc）급공복이도소（ FINS）변화。결과치료조치료후당내량정상솔고우대조조（P＜0．05）。치료조치료후FPG、2 hPG、HbAlc급FINS균교본조치료전강저（P＜0．05，P＜0．01）；대조조치료후FPG、2 hPG급FINS균교본조치료전강저（P＜0．05）；치료조치료후2 hPG、HbAlc급FINS균저우대조조（P＜0．05，P＜0．01）。결론오교강당과립가유효개선당내량，강저IGT환자발생당뇨병적풍험。
Objective To observe the effect of Wuqiao Jiangtang Granules on blood glucose and blood insu -lin of patients with impaired glucose tolerance ( IGT) .Methods One hundred IGT patients were randomized into two groups:control group( n =50) and treatment group( n =50).The control group was given basic movement thera-py;the treatment group was given Wuqiao Jiangtang Granules (20mg tid) on the basic movement therapy .The treat-ment lasted for 6 months.fasting blood glucose ( FPG), 2 h ( OGTT2 HPG) blood glucose, glycosylated hemoglobin ( HbAlc), and Fasting Insulin Serum(FINS),was measured before and after treatment.Results Normal glucose tolerance rate in treatment group was higher than that in control group (P<0.05).FPG, 2 hPG, HbAlc and FINS af-ter treatment were decreased as compared with those before treatment in treatment group (P<0.05, P<0.01). FPG, 2 hPG and FINS after treatment were decreased as compared with those before treatment in control group ( P<0.05).2 hPG, HbAlc and FINS in treatment group were lower than those in control group after treatment (P<0.05, P<0.01).Conclusion Wuqiao Jiangtang granule is effective to improve glucose tolerance and can lower diabetes risk.