南方医科大学学报
南方醫科大學學報
남방의과대학학보
JOURNAL OF SOUTHERN MEDICAL UNIVERSITY
2014年
6期
753-758
,共6页
张睿%许珉%张青%杨引通%陈彦飞
張睿%許珉%張青%楊引通%陳彥飛
장예%허민%장청%양인통%진언비
刺激声强度%前庭%眼肌前庭诱发肌源性电位%颈肌前庭诱发肌源性电位
刺激聲彊度%前庭%眼肌前庭誘髮肌源性電位%頸肌前庭誘髮肌源性電位
자격성강도%전정%안기전정유발기원성전위%경기전정유발기원성전위
stimulus intensity%vestibule%ocular vestibular-evoked myogenic potential%cervical vestibular-evoked myogenic potential
目的：了解刺激声强度差异对正常人气导短纯音诱发的眼肌前庭诱发肌源性电位（ocular vestibular-evoked myogenic potential, oVEMP）和颈肌前庭肌源性诱发电位（cervical vestibular-evoked myogenic potential, cVEMP）的影响。方法选择国人正常人35例作为研究对象，男16例，女19例，年龄4~40岁（20.80±8.89），以500Hz tone brust为刺激音，按照100、95、90、85、80、75 dB nHL依次进行气导oVEMP和cVEMP检测，计算VEMP在不同刺激声强度的引出率、nI潜伏期、pI潜伏期、nI-pI波间期、振幅值和AR值，进行波形参数计算和声强度组间对比。结果全组正常人oVEMP和cVEMP的阈值分别为86.5±4.37 dB nHL、83.57±4.52 dB nHL。随着刺激声强度的减弱，无论oVEMP还是cVEMP，均表现出引出率下降、振幅减低等特点。在刺激声强度为100 dB nHL和95 dB nHL时，oVEMP和cVEMP的引出率均为100%，两者之间图形参数差异并不显著。结论随着刺激声强度的减弱，oVEMP和cVEMP出现引出率下降、振幅减低的趋势。对于40岁以下的国人人群，建议采用95 dB nHL作为VEMPs测试的最大起始刺激强度。
目的：瞭解刺激聲彊度差異對正常人氣導短純音誘髮的眼肌前庭誘髮肌源性電位（ocular vestibular-evoked myogenic potential, oVEMP）和頸肌前庭肌源性誘髮電位（cervical vestibular-evoked myogenic potential, cVEMP）的影響。方法選擇國人正常人35例作為研究對象，男16例，女19例，年齡4~40歲（20.80±8.89），以500Hz tone brust為刺激音，按照100、95、90、85、80、75 dB nHL依次進行氣導oVEMP和cVEMP檢測，計算VEMP在不同刺激聲彊度的引齣率、nI潛伏期、pI潛伏期、nI-pI波間期、振幅值和AR值，進行波形參數計算和聲彊度組間對比。結果全組正常人oVEMP和cVEMP的閾值分彆為86.5±4.37 dB nHL、83.57±4.52 dB nHL。隨著刺激聲彊度的減弱，無論oVEMP還是cVEMP，均錶現齣引齣率下降、振幅減低等特點。在刺激聲彊度為100 dB nHL和95 dB nHL時，oVEMP和cVEMP的引齣率均為100%，兩者之間圖形參數差異併不顯著。結論隨著刺激聲彊度的減弱，oVEMP和cVEMP齣現引齣率下降、振幅減低的趨勢。對于40歲以下的國人人群，建議採用95 dB nHL作為VEMPs測試的最大起始刺激彊度。
목적：료해자격성강도차이대정상인기도단순음유발적안기전정유발기원성전위（ocular vestibular-evoked myogenic potential, oVEMP）화경기전정기원성유발전위（cervical vestibular-evoked myogenic potential, cVEMP）적영향。방법선택국인정상인35례작위연구대상，남16례，녀19례，년령4~40세（20.80±8.89），이500Hz tone brust위자격음，안조100、95、90、85、80、75 dB nHL의차진행기도oVEMP화cVEMP검측，계산VEMP재불동자격성강도적인출솔、nI잠복기、pI잠복기、nI-pI파간기、진폭치화AR치，진행파형삼수계산화성강도조간대비。결과전조정상인oVEMP화cVEMP적역치분별위86.5±4.37 dB nHL、83.57±4.52 dB nHL。수착자격성강도적감약，무론oVEMP환시cVEMP，균표현출인출솔하강、진폭감저등특점。재자격성강도위100 dB nHL화95 dB nHL시，oVEMP화cVEMP적인출솔균위100%，량자지간도형삼수차이병불현저。결론수착자격성강도적감약，oVEMP화cVEMP출현인출솔하강、진폭감저적추세。대우40세이하적국인인군，건의채용95 dB nHL작위VEMPs측시적최대기시자격강도。
Objective To observe the effect of acoustic stimulus intensity on air-conducted sound elicited ocular vestibular-evoked myogenic potential (oVEMP) and cervical vestibular-evoked myogenic potential (cVEMP) in normal young Chinese subjects. Methods Thirty-five normal subjects aged 4-40 years (20.80 ± 8.89 years), including 16 males and 19 females, were recruited for conventional oVEMP and cVEMP examinations. The responses obtained from each side using 500 Hz tone bursts were divided into 6 groups according to different sound intensities (100, 95, 90, 85, 80 and 75dB nHL). The response rate and normal parameters of each stimulus intensity group were calculated. Results As the acoustic stimulus intensity decreased, the oVEMP response rate decreased from 100%in both 100 dB nHL and 95dB nHL groups to 97.14%(90 dB nHL), 54.29%(85 dB nHL), 14.29%(80 dB nHL), and 2.86%(75 dB nHL), and the response rate of cVEMP, 100%in both 100 dB nHL and 95dB nHL groups, was lowered to 97.14%(90 dB nHL), 84.29%(85 dB nHL), 38.57%(80 dB nHL) and 8.57%(75 dB nHL). The response rate and the parameters were comparable between 100 and 95 dB nHL groups. Conclusion As the acoustic stimulus intensity decreases, both oVEMP and cVEMP show decreased response rate and amplitude. For Chinese subjects under 40 years of age, we recommend 95dB nHL as the maximum initial stimulus intensity in VEMPs test.
