CAJ | 학술논문

目的：通过对第三代头孢菌素类抗生素的不良反应分析，为提高临床合理安全使用抗生素提供参考。方法采用回顾性调查方法，利用Excel对收集的不良反应报告进行统计，对不良反应的药品、给药途径、临床表现等数据分类统计和分析。结果第三代头孢菌素类抗生素不良反应涉及药品11种，涉及最多不良反应的是头孢曲松和头孢哌酮。药品不良反应累及7个器官或系统，比例最高的是变态反应。结论应关注头孢菌素类抗生素不良反应，提高合理用药水平。
목적：통과대제삼대두포균소류항생소적불량반응분석，위제고림상합리안전사용항생소제공삼고。방법채용회고성조사방법，이용Excel대수집적불량반응보고진행통계，대불량반응적약품、급약도경、림상표현등수거분류통계화분석。결과제삼대두포균소류항생소불량반응섭급약품11충，섭급최다불량반응적시두포곡송화두포고동。약품불량반응루급7개기관혹계통，비례최고적시변태반응。결론응관주두포균소류항생소불량반응，제고합리용약수평。
Objective Through the analysis of adverse reactions to the third generation cephalosporin antibiotics, so as to provide reference for clinical rational use of antibiotics. Methods Using the method of retrospective investigation, and using Excellto collect adverse reaction reports and take statistics, to statistics and analysis the data of adverse reaction of drugs, routes of administration, clinical performance. Results The adverse reactions of the third generation of cephalosporin drugs related to 11 , involving the most adverse reaction of cefoperazone was rocephin and cefoperazone. Adverse drug reaction involved 7 organs or systems, and the highest proportion is allergic reaction. Conclusion We should pay attention to adverse reactions of cephalosporins to improve the level of rational use of drugs.